Evidence map›Paper›PMID 39252210›Full record

SynthesisJournal of oral rehabilitation2025

Tobacco smoking and its impact on pain intensity of temporomandibular disorders: A systematic review and metanalysis.

Amarshree A Shetty, Sultan Abdulrahman Almalki, AlBandary Hassan Al Jameel, Inderjit Murugendrappa Gowdar, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of oral rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amarshree A ShettyDepartment of Paediatric and Preventive Dentistry, A.B Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to Be University), Mangalore, Karnataka, India.
Sultan Abdulrahman AlmalkiDepartment of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin AbdulAziz University, Al-kharj, Saudi Arabia.
AlBandary Hassan Al JameelDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Inderjit Murugendrappa GowdarDepartment of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin AbdulAziz University, Al-kharj, Saudi Arabia.
Vincenzo RonsivalleDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, Catania, Italy.
Marco CicciùDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, Catania, Italy.
Giuseppe MinerviniSaveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemporomandibular disorders (TMDs) encompass a spectrum of orofacial conditions characterised by pain and dysfunction in the temporomandibular joint and surrounding structures. Tobacco smoking has been posited as a potential factor influencing the prevalence and intensity of TMD. However, the nature and extent of this relationship remain unclear due to variations in study outcomes. This systematic review aimed to consolidate existing research findings to elucidate the association between tobacco smoking and TMD pain intensity.

methodsA comprehensive search of electronic databases was conducted to identify relevant studies published up to June 2023. Studies investigating the relationship between tobacco smoking and TMD pain were included. Data extraction was conducted by two reviewers. Quality assessment was performed using the New Castle-Ottawa scale. Review Manager 5.4 was used to quantitatively analyse the results.

resultsThe review included four studies employing similar TMD assessment techniques. All studies reported elevated TMD pain intensity among tobacco users, with non-smokers exhibiting lower pain intensity. The quality of the included studies was good. Meta-analytic results showed that TMD pain intensity was higher in the smokers group compared to the non-smokers group, with a weighted mean difference (WMD) of 0.65 (BPM) (95% CI: [0.10, 1.19], p = .02).

conclusionThis systematic review provides a comprehensive synthesis of the existing literature on tobacco smoking and TMD symptoms. The findings underscore the multifaceted nature of the relationship between smoking and TMD pain, highlighting its clinical relevance and the need for tailored interventions. Further research is warranted to elucidate underlying mechanisms and potential moderating factors, contributing to a more nuanced understanding of this complex association.

Indexed as

Facial PainTemporomandibular Joint DisordersTobacco SmokingHumansPain Measurementorofacial painpain intensitytemporomandibular disorderstobacco smoking

Identifiers

PMID39252210
PMCPMC11740265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.