Evidence map›Paper›PMID 39252005›Full record

Trial reportBMC health services research2024

Improving access to tuberculosis preventive treatment for children in Ethiopia: designing a home-based contact management intervention for the CHIP-TB trial through formative research.

Nicole Salazar-Austin, Alanna J Bergman, Christiaan Mulder, Carrie Tudor, Fiseha Mulatu, Gidea Conradie, Richard E Chaisson, Jonathan E Golub, Gavin Churchyard, Ahmed Bedru and 1 more

2 registry-linked trialsAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04369326 nacompletednot on this map

Community Initiated Preventive Therapy for TB (CHIP-TB Trial)

TypeinterventionalSponsorJohns Hopkins UniversityRan2021 to 2023Enrolled1,168ConditionsTuberculosisArmsCommunity-Based TPT Initiation
NCT04494516 completednot on this map

A Qualitative Study to Optimize a Community-Based Pediatric TB/HIV Prevention Intervention and Implementation Strategy

TypeobservationalSponsorJohns Hopkins UniversityRan2021 to 2023Enrolled183ConditionsTuberculosis Infection, Tuberculosis Prevention
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicole Salazar-AustinDepartment of Pediatrics, Johns Hopkins University School of Medicine, 200 N. Wolfe Street Room 3147, Baltimore, MD, 21287, USA. nsalaza1@jhmi.edu.
Alanna J BergmanJohns Hopkins Center for Infectious Disease and Nursing Innovation, Baltimore, MD, USA.
Christiaan MulderDepartment of TB Elimination and Health System Innovations, KNCV Tuberculosis Foundation, The Hague, The Netherlands.
Carrie TudorJohns Hopkins Center for Infectious Disease and Nursing Innovation, Baltimore, MD, USA.
Fiseha MulatuKNCV Ethiopia, Addis Ababa, Ethiopia.
Gidea ConradieThe Aurum Institute, Johannesburg, South Africa.
Richard E ChaissonDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jonathan E GolubDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Gavin ChurchyardThe Aurum Institute, Johannesburg, South Africa.
Ahmed BedruKNCV Ethiopia, Addis Ababa, Ethiopia.
Deanna KerriganDepartment of Prevention and Community Health, George Washington University Milken Institute School of Public Health, Washington D.C., USA.

Funding

Task-Shifting Pediatric TB/HIV Prevention to Community Health Workers in South AfricaK23HD096973 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SALAZAR-AUSTIN, NICOLE · 2019 to 2022
$682k
Exploring the Impact of Illness Identity on Intersectional Stigma Through the Care ContinuumF31NR020588 · NINR · JOHNS HOPKINS UNIVERSITY · PI BERGMAN, ALANNA J · 2022 to 2023
$88k
National Institute of Child Health and Human Development K23HD096973NICHD NIH HHS K23 HD096973NINR NIH HHS F31 NR020588NINR NIH HHS F31NR020588UNITAID IMPAACT4TB
6 · The paper itself

Abstract

backgroundTuberculosis (TB) preventive treatment (TPT) is a long-standing recommendation for children exposed to TB but remains poorly implemented. Home-based contact management may increase access and coverage of TPT among children exposed to TB in their households.

methodsSixty in-depth interviews were conducted with key informants including program managers, TB providers (known as TB focal persons), health extension workers and caregivers whose children had recently engaged with TB prevention services in Oromia, Ethiopia in 2021 to understand the barriers and facilitators to providing home-based TB prevention services for children aged < 15 years. Thematic content analysis was conducted including systematically coding each interview.

resultsHome-based services were considered a family-centered intervention, addressing the time and financial constraints of clients. Stakeholders proposed a task-shared intervention between health extension workers and facility-based TB focal persons. They recommended that TB services be integrated into other home-based services, including HIV, nutrition, and vaccination services to reduce workload on the already overstretched health extension workers. Community awareness was considered essential to improve acceptability of home-based services and TPT in general among community members.

conclusionsDecentralization of TPT should be supported by task-sharing initiation and follow up between health extension workers and facility-based TB focal persons and integration of home-based services. Active community engagement through several existing mechanisms can help improve acceptability for both home-based interventions and TPT promotion overall for children.

trial registrationThe results presented here were from formative research related to the CHIP-TB Trial (Identifier NCT04369326) registered on April 30, 2020. This qualitative study was separately registered at NCT04494516 on 27 July 2020.

Indexed as

Health Services AccessibilityTuberculosisAdolescentCaregiversChildChild, PreschoolEthiopiaFemaleHome Care ServicesHumansInfantInterviews as TopicMaleQualitative ResearchCommunity health workerHome-basedTuberculosis prevention

Identifiers

PMID39252005
PMCPMC11386379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.