Evidence map›Paper›PMID 39252002›Full record

Observational studyCardiovascular diabetology2024

High proportion of undiagnosed diabetes in patients surgically treated for infrarenal abdominal aortic aneurysm: findings from the multicentre Norwegian Aortic Aneurysm and Diabetes (ABANDIA) Study.

J Wesche, T Bakken, M Vetrhus, K O Hufthammer, L Aa Nyroenning, H Fagertun, I Saethre, B H Wold, C Lyng, E M Pettersen and 9 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

J WescheUniversity of Oslo, Oslo, Norway.
T BakkenDepartment of Vascular Surgery, Vestfold Hospital Trust Tønsberg, Tønsberg, Norway.
M VetrhusDepartment of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.
K O HufthammerCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway.
L Aa NyroenningDepartment of Circulation and Medical Imaging, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.
H FagertunDepartment of Circulation and Medical Imaging, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.
I SaethreDepartment of Vascular Surgery, University Hospital of North Norway, Tromsø, Norway.
B H WoldDepartment of Vascular Surgery, Nordland Hospital Trust Bodø, Bodø, Norway.
C LyngDepartment of Vascular Surgery, Innlandet Hospital Trust Hamar, Hamar, Norway.
E M PettersenDepartment of Circulation and Medical Imaging, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.
I S KjellsenDepartment of Vascular Surgery, Stavanger University Hospital, Stavanger, Norway.
E T GubberudDepartment of Vascular Surgery, Clinic of Surgery, Haukeland University Hospital, Bergen, Norway.
S KiilDepartment of Vascular Surgery, Vestre Viken Hospital Trust Drammen, Drammen, Norway.
H LooseDepartment of Vascular Surgery, Oslo University Hospital Ullevaal and Aker, Oslo, Norway.
M T HelgelandDepartment of Vascular Surgery, Akershus University Hospital, Lørenskog, Norway.
M E AltreutherDepartment of Circulation and Medical Imaging, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.
E MattssonDepartment of Circulation and Medical Imaging, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.
T JonungDepartment of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.
I D HjellestadDepartment of Laboratory Medicine and Pathology, Hormone Laboratory, Haukeland University Hospital, Postbox 1400, 5021, Bergen, Norway. Iren.hjellestad@gmail.com.

Funding

Finn Wilhelmsens stiftelse Org. nr. 992 110 813 c/o UNIFOR Postboks 1131 Blindern 0317 Oslo Avd.941Helse Vest RHT (the Western Norway Regional Health Authority) 240774
6 · The paper itself

Abstract

backgroundThe aim was to investigate the total prevalence of known and undiagnosed diabetes mellitus (DM), and the association of DM with perioperative complications following elective, infrarenal, open surgical (OSR) or endovascular (EVAR), Abdominal Aortic Aneurysm (AAA) repair.

methodsIn this Norwegian prospective multicentre study, 877 patients underwent preoperative screening for DM by HbA

resultsThe total prevalence of DM was 15% (95% CI 13%,17%), of which 25% of the DM cases (95% CI 18%,33%) were undiagnosed upon admission for AAA surgery. The OSR to EVAR ratio was 52% versus 48%, with similar distribution among DM patients, and no differences in the prevalence of known and undiagnosed DM in the EVAR versus the OSR group. Total 30-day mortality rate was 0.6% (5/877). Sixty-six organ-related complications occurred in 58 (7%) of the patients. DM was not statistically significantly associated with a higher risk of in-hospital organ-related complications (OR 1.23, 95% CI 0.57,2.39, p = 0.57), procedure-related complications (OR 1.48, 95% CI 0.79,2.63, p = 0.20), 30-day mortality (p = 0.09) or length of stay (HR 1.06, 95% CI 0.88,1.28, p = 0.54). According to post-hoc-analyses, organ-related complications were more frequent in patients with newly diagnosed DM (n = 32) than in non-DM patients (OR 4.92; 95% CI 1.53,14.3, p = 0.005).

conclusionTwenty-five percent of all DM cases were undiagnosed at the time of AAA surgery. Based on post-hoc analyses, undiagnosed DM seems to be associated with an increased risk of organ related complications following AAA surgery. This study suggests universal DM screening in AAA patients to reduce the number of DM patients being undiagnosed and to improve proactive diabetes care in this population. The results from post-hoc analyses should be confirmed in future studies.

Indexed as

Aortic Aneurysm, AbdominalBiomarkersDiabetes MellitusEndovascular ProceduresPostoperative ComplicationsAgedAged, 80 and overBlood Vessel Prosthesis ImplantationFemaleGlycated HemoglobinHospital MortalityHumansLength of StayMaleMiddle AgedNorwayBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanAbdominal aortic aneurysm (AAA)Diabetes mellitus (DM)Endovascular aneurysm repair (EVAR)Infrarenal AAA repairOpen surgical aneurysm repair (OSR)

Identifiers

PMID39252002
PMCPMC11386390

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.