Evidence map›Paper›PMID 39251985›Full record

ArticleRespiratory research2024

Characteristics of lung resistance and elastance associated with tracheal stenosis and intrapulmonary airway narrowing in ex vivo sheep lungs.

Yuto Yasuda, Geoffrey N Maksym, Lu Wang, Pasquale Chitano, Chun Y Seow

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuto YasudaCentre for Heart Lung Innovation, St. Paul's Hospital, Providence Health Care, University of British Columbia, 1081 Burrard Street, Rm 166, Vancouver, BC, V6Z 1Y6, Canada.
Geoffrey N MaksymSchool of Biomedical Engineering, Dalhousie University, 6299 South St, Halifax, NS, B3H 4R2, Canada.
Lu WangCentre for Heart Lung Innovation, St. Paul's Hospital, Providence Health Care, University of British Columbia, 1081 Burrard Street, Rm 166, Vancouver, BC, V6Z 1Y6, Canada.
Pasquale ChitanoCentre for Heart Lung Innovation, St. Paul's Hospital, Providence Health Care, University of British Columbia, 1081 Burrard Street, Rm 166, Vancouver, BC, V6Z 1Y6, Canada.
Chun Y SeowCentre for Heart Lung Innovation, St. Paul's Hospital, Providence Health Care, University of British Columbia, 1081 Burrard Street, Rm 166, Vancouver, BC, V6Z 1Y6, Canada. chun.seow@hli.ubc.ca.

Funding

CIHR PJT-183783
6 · The paper itself

Abstract

backgroundUnderstanding the characteristics of pulmonary resistance and elastance in relation to the location of airway narrowing, e.g., tracheal stenosis vs. intrapulmonary airway obstruction, will help us understand lung function characteristics and mechanisms related to different airway diseases.

methodsIn this study, we used ex vivo sheep lungs as a model to measure lung resistance and elastance across a range of transpulmonary pressures (5-30 cmH

resultsWe found a pattern change in the lung resistance and apparent lung elastance as functions of ventilation frequency that depended on the transpulmonary pressure (or lung volume). At a transpulmonary pressure of 10 cmH

conclusionsResults from this study suggest that lung resistance and apparent elastance measured at 10 cmH

Indexed as

Airway ResistanceLungTracheal StenosisAnimalsDisease Models, AnimalElasticityIn Vitro TechniquesSheepAirway smooth muscleCentral airway obstructionLung mechanicsPeripheral airway narrowingTranspulmonary pressureVentilation frequency

Identifiers

PMID39251985
PMCPMC11385140

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.