ArticleScientific reports2024
Long-term outcome and predictors of neurological recovery in cervical spinal cord injury: a population-based cohort study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The role of sex hormones in neurological and functional recovery following spinal cord injury in females: a systematic review of the literature.Spinal cord · 2026Pooled it
- Duraplasty in acute spinal cord injury: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Article
- Radiologically Devastating Yet Neurologically Intact: A Rare Case of Ambulatory C6-C7 Translational Injury with Bilateral Facet Dislocation and Vertebral Artery Thrombosis.Journal of orthopaedic case reports · 2026Article
- Inpatient Outcomes in Geriatric Complete Cervical Spinal Cord Injury: Associations Between Surgical Management and Reduced Mortality Despite Increased Morbidity.Global spine journal · 2026Article
- Quality of life after spinal cord injury: a qualitative interview-based study.Spinal cord series and cases · 2026Article
- Temporal trends in gabapentinoid use for the acute management of spinal cord injury: a retrospective cohort study.Spinal cord · 2026Article
- Patterns of injury, management stratification, and inpatient outcomes in pediatric complete cervical spinal cord injury: insights from a national database.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Awake closed manual reduction of cervical spine dislocation as an emergency bridge to surgery: a case report.Frontiers in medicine · 2026Article
- Multi-Channel Functional Electrical Stimulation to Improve Specificity of Hand Extension.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Analyzing and Assisting Finger Motions for Spoon Scooping.Biomimetics (Basel, Switzerland) · 2025Article
- Impact of early decompression surgery and injury characteristics on neurological recovery following traumatic cervical spinal cord injury.Brain & spine · 2025Article
- Characterizing Neurologic Recovery after Acute Complete Traumatic Spinal Cord Injury in Relation to Hemodynamic Management with Lumbar Intrathecal Drains.Neurotrauma reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This retrospective study analyzed prognostic factors for neurological improvement and ambulation in 194 adult patients (≥ 15 years) with traumatic cervical spinal cord injuries treated at the neurological SCI unit (SCIU) at the Karolinska University Hospital Stockholm, Sweden, between 2010 and 2020. The primary outcome was American spinal injury association impairment scale (AIS) improvement, with secondary focus on ambulation restoration. Results showed 41% experienced AIS improvement, with 51% regaining ambulation over a median follow-up of 3.7 years. Significant AIS improvement (p < 0.001) and reduced bladder/bowel dysfunction (p < 0.001) were noted. Multivariable analysis identified initial AIS C-D (< 0.001), central cord syndrome (p = 0.016), and C0-C3 injury (p = 0.017) as positive AIS improvement predictors, while lower extremity motor score (LEMS) (p < 0.001) and longer ICU stays (p < 0.001) were negative predictors. Patients with initial AIS C-D (p < 0.001) and higher LEMS (p < 0.001) were more likely to regain ambulation. Finally, older age was a negative prognostic factor (p = 0.003). In conclusion, initial injury severity significantly predicted neurological improvement and ambulation. Recovery was observed even in severe cases, emphasizing the importance of tailored rehabilitation for improved outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.