Evidence map›Paper›PMID 39251774›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2024

Leveraging ultra-high field (7T) MRI in psychiatric research.

Finnegan J Calabro, Ashley C Parr, Valerie J Sydnor, Hoby Hetherington, Konasale M Prasad, Tamer S Ibrahim, Deepak K Sarpal, Alyssa Famalette, Piya Verma, Beatriz Luna

Erratum issuedAbstract readReview
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Frozen emotions, frozen bodies: a systematic review of limbic system alterations in catatonia.European archives of psychiatry and clinical neuroscience · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Finnegan J CalabroDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. fjc20@pitt.edu.
Ashley C ParrDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Valerie J SydnorDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Hoby HetheringtonResonance Research Inc., Billerica, MA, USA.
Konasale M PrasadDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-0245-1393
Tamer S IbrahimDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Deepak K SarpalDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-5842-6782
Alyssa FamaletteDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Piya VermaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Beatriz LunaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Refinement of Brain Mechanisms Underlying the Developmental Stabilization from Adolescent to Adult Neurocognitive ProcessingR01MH067924 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BEATRIZ LUNA · 2004 to 2026
$14.0M
Plasticity of Auditory Cortical Circuits in SchizophreniaR01MH071533 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 2004 to 2018
$6.9M
Training for Transformative Discovery in PsychiatryT32MH016804 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 1985 to 2025
$6.2M
A Multidimensional Dissection of Antipsychotic Treatment Response in Early SchizophreniaR01MH124705 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Deepak K Sarpal · 2021 to 2026
$3.3M
NIMH NIH HHS R01 MH067924NIMH NIH HHS R01 MH071533NIMH NIH HHS R01 MH124705NIMH NIH HHS T32 MH016804U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) MH067924
6 · The paper itself

Abstract

Non-invasive brain imaging has played a critical role in establishing our understanding of the neural properties that contribute to the emergence of psychiatric disorders. However, characterizing core neurobiological mechanisms of psychiatric symptomatology requires greater structural, functional, and neurochemical specificity than is typically obtainable with standard field strength MRI acquisitions (e.g., 3T). Ultra-high field (UHF) imaging at 7 Tesla (7T) provides the opportunity to identify neurobiological systems that confer risk, determine etiology, and characterize disease progression and treatment outcomes of major mental illnesses. Increases in scanner availability, regulatory approval, and sequence availability have made the application of UHF to clinical cohorts more feasible than ever before, yet the application of UHF approaches to the study of mental health remains nascent. In this technical review, we describe core neuroimaging methodologies which benefit from UHF acquisition, including high resolution structural and functional imaging, single (

Indexed as

BrainMagnetic Resonance ImagingMental DisordersHumansNeuroimaging

Identifiers

PMID39251774
PMCPMC11525672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.