Evidence map›Paper›PMID 39251742›Full record

ArticleLeukemia2024

Early-life tobacco exposure is causally implicated in aberrant RAG-mediated recombination in childhood acute lymphoblastic leukemia.

Tanxin Liu, Keren Xu, Anmol Pardeshi, Swe Swe Myint, Alice Y Kang, Libby M Morimoto, Michael R Lieber, Joseph L Wiemels, Scott C Kogan, Catherine Metayer and 1 more

Abstract read
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Tanxin LiuCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Keren XuCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Anmol PardeshiCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Swe Swe MyintCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-2430-088X
Alice Y KangSchool of Public Health, University of California Berkeley, Berkeley, CA, USA.
Libby M MorimotoSchool of Public Health, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-1509-739X
Michael R LieberDepartments of Pathology, Biochemistry, Molecular Microbiology & Immunology, and Section of Molecular & Computational Biology (Department of Biological Sciences), University of Southern California, Los Angeles, CA, USA.
Joseph L WiemelsCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-4838-9951
Scott C KoganDepartment of Laboratory Medicine, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2395-8479
Catherine MetayerSchool of Public Health, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-3467-4145
Adam J de SmithCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA. desmith@usc.edu.ORCID http://orcid.org/0000-0003-4880-7543

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SMITH, MARTYN T · 1987 to 2025
$74.6M
Environmental and Molecular Epidemiology of Childhood LeukemiaR01ES009137 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 1999 to 2013
$21.1M
Site-Specific Recombination in Human Health & DiseaseR35GM118009 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LIEBER, MICHAEL R · 2016 to 2025
$4.4M
Project 3 - Prenatal Exposures, Constitutive Genetics, DNA Methylation & Childhood LeukemiaP50ES018172 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 2015 to 2019
$3.8M
Project 3: Prenatal Exposure, DNA Methylation & Childhood LeukemiaP01ES018172 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 2009 to 2013
$3.7M
Support For Infrastructure of Childhood Leukemia Environmental ResearchR24ES028524 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Catherine Metayer · 2017 to 2026
$2.3M
Support For Infrastructure of Childhood Leukemia Environmental ResearchU24ES028524 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 2023 to 2025
$1.1M
Leukemia and Lymphoma Society (Leukemia & Lymphoma Society) Scholar Award (1390-24)NIEHS NIH HHS P01 ES018172NIEHS NIH HHS P42 ES004705NIEHS NIH HHS P50 ES018172NIEHS NIH HHS R01 ES009137NIEHS NIH HHS R24 ES028524NIEHS NIH HHS U24 ES028524NIGMS NIH HHS R35 GM118009Tobacco-Related Disease Research Program (TRDRP) 26IR-0005AU.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) P01ES018172U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) P42ES004705U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) P50ES018172U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) R01ES009137U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) R24ES028524U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) U24ES028524U.S. Environmental Protection Agency (US Environmental Protection Agency) RD83451101U.S. Environmental Protection Agency (US Environmental Protection Agency) RD83615901
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39251742
PMCPMC11518992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.