Evidence map›Paper›PMID 39251652›Full record

ArticleScientific reports2024

Veillonella parvula as an anaerobic lactate-fermenting bacterium for inhibition of tumor growth and metastasis through tumor-specific colonization and decrease of tumor's lactate level.

Amirhosein Kefayat, Mahshid Bahrami, Mojtaba Karami, Soodabeh Rostami, Fatemeh Ghahremani

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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    Article
  5. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amirhosein KefayatDepartment of Oncology, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran.
Mahshid BahramiDepartment of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mojtaba KaramiDepartment of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.
Soodabeh RostamiNosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran.
Fatemeh GhahremaniDepartment of Medical Physics and Radiotherapy, Arak University of Medical Sciences, Sardasht, Meydan Basij, Arāk, 38481-76941, Iran. bahare.ghahremani@gmail.com.

Funding

Arak University of Medical Sciences 67354
6 · The paper itself

Abstract

High tumor's lactate level directly associates with high tumor growth, metastasis, and patients' poor prognosis. Therefore, many studies have focused on the decrease of tumor's lactate as a novel cancer treatment. In the present study for the first time, a strictly anaerobic lactate-fermenting bacterium, Veillonella parvula, was employed for the decrease of tumor's lactate level. At first, 4T1 breast tumor-bearing BALB/c mice were administered with 10

Indexed as

Lactic AcidMice, Inbred BALB CVeillonellaAnimalsBreast NeoplasmsCell Line, TumorFemaleMiceNeoplasm MetastasisLactic AcidBacteria therapyBreast cancerLactateVeillonella parvula

Identifiers

PMID39251652
PMCPMC11385575

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.