Evidence map›Paper›PMID 39251640›Full record

ArticleScientific data2024

The Aphasia Recovery Cohort, an open-source chronic stroke repository.

Makayla Gibson, Roger Newman-Norlund, Leonardo Bonilha, Julius Fridriksson, Gregory Hickok, Argye E Hillis, Dirk-Bart den Ouden, Christopher Rorden

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Topography and functional connectivity analysis of heart surgery-associated brain lesions: a literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Accelerated brain aging and anterior white matter hyperintensity burden in chronic post-stroke aphasia: a lesion-aware MRI analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Acute-Phase Machine Learning Prediction of 12-Month Aphasia and Discourse Recovery.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Comparison of Large Language Model with Aphasia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Makayla GibsonDepartment of Psychology, University of South Carolina, Columbia, SC, USA.ORCID 0000-0001-7309-8713
Roger Newman-NorlundDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
Leonardo BonilhaDepartment of Neurology, University of South Carolina School of Medicine, Columbia, SC, USA.
Julius FridrikssonDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC, USA.
Gregory HickokDepartment of Cognitive Sciences, University of California, Irvine, CA, USA.
Argye E HillisDepartment of Neurology, John Hopkins University, Baltimore, MD, USA.
Dirk-Bart den OudenDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC, USA.ORCID 0000-0001-6971-7606
Christopher RordenDepartment of Psychology, University of South Carolina, Columbia, SC, USA. rorden@sc.edu.

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BONILHA, LEONARDO F · 2016 to 2025
$25.0M
Trans-cranial Direct Current Stimulation to Treat Aphasia: Phase II TrialU01DC011739 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2012 to 2016
$4.4M
Extending ezBIDS, NiiVue and dcm2niix for user-friendly cloud-based integration and visualizationRF1MH133701 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RORDEN, CHRISTOPHER · 2023 to 2023
$2.0M
Neural Predictors of Anomia Recovery in AphasiaR01DC008355 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2007 to 2011
$1.7M
NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC008355NIDCD NIH HHS U01 DC011739NIMH NIH HHS RF1 MH133701U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) RF1MH133701U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) P50DC014664U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) R01DC008355U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) U01DC011739
6 · The paper itself

Abstract

Sharing neuroimaging datasets enables reproducibility, education, tool development, and new discoveries. Neuroimaging from many studies are publicly available, providing a glimpse into progressive disorders and human development. In contrast, few stroke studies are shared, and these datasets lack longitudinal sampling of functional imaging, diffusion imaging, as well as the behavioral and demographic data that encourage novel applications. This is surprising, as stroke is a leading cause of disability, and acquiring brain imaging is considered standard of care. The first release of the Aphasia Recovery Cohort includes imaging data, demographics and behavioral measures from 230 chronic stroke survivors who experienced aphasia. We also share scripts to illustrate how the imaging data can predict impairment. In conclusion, recent advances in machine learning thrive on large, diverse datasets. Clinical data sharing can contribute to improvements in automated detection of brain injury, identification of white matter hyperintensities, measures of brain health, and prognostic abilities to guide care.

Indexed as

AphasiaStrokeBrainCohort StudiesFemaleHumansMaleNeuroimaging

Identifiers

PMID39251640
PMCPMC11384737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.