Evidence map›Paper›PMID 39251627›Full record

ArticleNPJ systems biology and applications2024

EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information.

Chuan Wang, Jiangyuan Wang, Wenjun Song, Guanzheng Luo, Taijiao Jiang

Abstract read
In one paragraph

Article in NPJ systems biology and applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Improving B-cell epitope prediction.Drug discovery today · 2025
    Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuan Wang *School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Jiangyuan Wang *Guangzhou National Laboratory, Guangzhou, China.
Wenjun SongGuangzhou National Laboratory, Guangzhou, China.
Guanzheng LuoSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China. luogzh5@mail.sysu.edu.cn.
Taijiao JiangGuangzhou National Laboratory, Guangzhou, China. taijiaobioinfor@ism.cams.cn.ORCID http://orcid.org/0000-0002-6280-6347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of antibody-specific epitopes on virus proteins is crucial for vaccine development and drug design. Nonetheless, traditional wet-lab approaches for the identification of epitopes are both costly and labor-intensive, underscoring the need for the development of efficient and cost-effective computational tools. Here, EpiScan, an attention-based deep learning framework for predicting antibody-specific epitopes, is presented. EpiScan adopts a multi-input and single-output strategy by designing independent blocks for different parts of antibodies, including variable heavy chain (V

Indexed as

Epitope MappingEpitopesSARS-CoV-2Antibodies, ViralComputational BiologyCOVID-19Deep LearningHumansSoftwareSpike Glycoprotein, CoronavirusAntibodies, ViralEpitopesSpike Glycoprotein, Coronavirus

Identifiers

PMID39251627
PMCPMC11383971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.