Evidence map›Paper›PMID 39251524›Full record

ArticleIrish journal of medical science2024

No difference in 6-month functional outcome between early and late decompressive craniectomies following acute ischaemic stroke in a national neurosurgical centre: a single-centre retrospective case-cohort study.

Adina S Nesa, Conor Gormley, Christopher Read, Sarah Power, Donncha O'Brien, Darragh Herlihy, Karl Boyle, Caroline M Larkin

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Article in Irish journal of medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Adina S NesaDepartment of Anaesthetics and Intensive Care Medicine, Beaumont Hospital, Dublin, Ireland.
Conor GormleyDepartment of Anaesthetics and Intensive Care Medicine, Beaumont Hospital, Dublin, Ireland.
Christopher ReadDepartment of Anaesthetics and Intensive Care Medicine, Beaumont Hospital, Dublin, Ireland.
Sarah PowerDepartment of Neuroradiology, Beaumont Hospital, Dublin, Ireland.
Donncha O'BrienDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Darragh HerlihyDepartment of Neuroradiology, Beaumont Hospital, Dublin, Ireland.
Karl BoyleDepartment of Geriatric and Stroke Medicine, Beaumont Hospital, Dublin, Ireland.
Caroline M LarkinDepartment of Anaesthetics and Intensive Care Medicine, Beaumont Hospital, Dublin, Ireland. carolinelarkin@beaumont.ie.ORCID http://orcid.org/0000-0001-5373-3978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecompressive craniectomies (DCs) are recommended for the treatment of raised intracranial pressure after acute ischaemic stroke. Some studies have demonstrated improved outcomes with early decompressive craniectomy (< 48 h from onset) in patients with malignant cerebral oedema following middle cerebral artery infarction. Limited data is available on suboccipital decompressive craniectomy after cerebellar infarction.

aimsOur primary objective was to determine whether the timing of DCs influenced functional outcomes at 6 months. Our secondary objectives were to analyse whether age, gender, the territory of stroke, or preceding thrombectomy impacts functional outcome post-DC.

methodsWe conducted a retrospective study of patients admitted between January 2014 and December 2020 who had DCs post-acute ischaemic stroke. Data was collected from ICU electronic records, individual patient charts, and the stroke database.

resultsTwenty-six patients had early DC (19 anterior/7 posterior) and 21 patients had late DC (17 anterior/4 posterior). There was no difference in the modified Rankin Scale (mRS) score of the two groups at 90 (p = 0.318) and 180 (p = 0.333) days post early vs late DC. Overall outcomes were poor, with 5 out of 46 patients (10.9%) having a mRS score ≤ 3 at 6 months. There was no difference in mRS scores between the patients who had hemicraniectomies for anterior circulation stroke (n = 35) and suboccipital DC for posterior circulation stroke (n = 11) (p = 0.594).

conclusionIn this single-centre retrospective study, we found no significant difference in functional outcomes between patients who had early or late DC after ischaemic stroke.

Indexed as

Decompressive CraniectomyIschemic StrokeAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTime FactorsTreatment OutcomeAcute ischaemic strokeDecompressive craniectomiesModified Rankin scale

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.