Evidence map›Paper›PMID 39251446›Full record

ArticleEuropean journal of pediatrics2024

Adiponectin concentration and cardiometabolic risk factors: the moderator role of cardiorespiratory fitness in adolescents.

Maiara Cristina Tadiotto, Patricia Ribeiro Paes Corazza, Francisco Jose de Menezes-Junior, Tatiana Aparecida Affornali Tozo, Maria de Fátima Aguiar Lopes, Juliana Pizzi, Larissa Rosa da Silva, Wendell Arthur Lopes, Neiva Leite

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Article in European journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maiara Cristina TadiottoDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil. mctadiotto@gmail.com.ORCID http://orcid.org/0000-0002-6953-0793
Patricia Ribeiro Paes CorazzaDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0001-7910-2445
Francisco Jose de Menezes-JuniorDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0003-4389-1213
Tatiana Aparecida Affornali TozoDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0002-9824-6206
Maria de Fátima Aguiar LopesDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0001-7571-9181
Juliana PizziDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0002-1560-3774
Larissa Rosa da SilvaCollegiate of Physical Education, State University of Western Paraná, Cascavel, Paraná, Brazil.ORCID http://orcid.org/0000-0003-3111-5364
Wendell Arthur LopesDepartment of Physical Education, State University of Maringá, Maringá, Paraná, Brazil.ORCID http://orcid.org/0000-0001-7895-6799
Neiva LeiteDepartment of Physical Education, Federal University of Paraná, Street Col. Francisco H. Dos Santos, 100, Jardim das Americas, Curitiba, Paraná, 81531-980, Brazil.ORCID http://orcid.org/0000-0002-4752-6697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to examine the moderating role of cardiorespiratory fitness (CRF) between the relationship of cardiometabolic risk factors and adiponectin in adolescents. This is a cross-sectional study conducted with 255 adolescents of both sexes, aged 11 to 17 years. Anthropometric and biochemical parameters such as body mass, height, fat mass (FM), fat-free mass, high-density lipoprotein, low-density lipoprotein, triglycerides, glucose, insulin, adiponectin, systolic blood pressure, diastolic blood pressure, and peak oxygen consumption (VO2peak) were measured. Body mass index z-score (BMI-z), tri-ponderal mass index (TMI), homeostasis model assessment insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), and age peak height velocity were calculated. The moderation analyses were tested using linear regression models. Interaction was observed with low CRF, indicating that those who achieved more than 2.27 (BMI-z), 2.18 (TMI), 2.10 (FM), 2.57 (insulin), 2.65 (HOMA-IR), and 2.81 (QUICKI) in L·min-1 on the CRF test may experience reduced risks in cardiometabolic risk factors.

conclusionThe deleterious effects attributed to excess adiposity and unfavorable changes related to insulin resistance and sensitivity may be attenuated by CRF. WHAT IS KNOWN: • Adiponectin, a protein derived from adipose tissue, may play a role as a potential marker of protection and predictor of cardiometabolic disorders and its relationship with cardiorespiratory fitness is controversial. WHAT IS NEW: • The deleterious effects attributed to overweight and unfavorable changes related to insulin resistance and sensitivity may be attenuated by high cardiorespiratory fitness in adolescents.

Indexed as

AdiponectinCardiometabolic Risk FactorsCardiorespiratory FitnessAdolescentBiomarkersChildCross-Sectional StudiesFemaleHumansInsulin ResistanceMaleRisk FactorsAdiponectinBiomarkersAdipokinesAdolescentsCardiometabolic riskCardiorespiratory fitnessPhysical fitnessRisk factors

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.