Evidence map›Paper›PMID 39251426›Full record

ArticleAnalytical and bioanalytical chemistry2024

Establishment of genomic RNA reference materials for BCR-ABL1 P210 measurement.

Yi Yang, Xia Wang, Chunyan Niu, Shujun Zhou, Huafang Gao, Xiaohua Jin, Shangjun Wang, Meihong Du, Xiaoyan Cheng, Lingxiang Zhu and 1 more

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yi YangCenter for Advanced Measurement Science, National Institute of Metrology, Beijing, 100029, China.
Xia WangCenter for Advanced Measurement Science, National Institute of Metrology, Beijing, 100029, China.
Chunyan NiuCenter for Advanced Measurement Science, National Institute of Metrology, Beijing, 100029, China.
Shujun ZhouShenzhen Institute for Technology Innovation, National Institute of Metrology, Shenzhen, 518107, China.
Huafang GaoNational Research Institute for Family Planning, Beijing, 100081, China.
Xiaohua JinNational Research Institute for Family Planning, Beijing, 100081, China.
Shangjun WangNanjing Institute of Measurement and Testing Technology, Nanjing, 210049, Jiangsu, China.
Meihong DuInstitute of Analysis and Testing, Beijing Academy of Science and Technology (Beijing Center for Physical and Chemical Analysis), Beijing, 100094, China.
Xiaoyan ChengInstitute of Analysis and Testing, Beijing Academy of Science and Technology (Beijing Center for Physical and Chemical Analysis), Beijing, 100094, China.
Lingxiang ZhuTargetingOne Co., Ltd., Beijing, 102299, China.
Lianhua DongCenter for Advanced Measurement Science, National Institute of Metrology, Beijing, 100029, China. donglh@nim.ac.cn.

Funding

National Key Research and Development Program of China 2023YFF0613300
6 · The paper itself

Abstract

Quantitation of BCR-ABL1 with the quantitative reverse transcriptase polymerase chain reaction (RT-PCR) is very important in monitoring chronic myeloid leukemia (CML), which relies on an RNA reference material. A genomic RNA reference material (RM) containing the BCR-ABL1 P210 fusion mutation was developed, and an absolute quantitative method based on one-step reverse transcription digital PCR (RT-dPCR) was established for characterizing the RM. The proposed dPCR method demonstrates high accuracy and excellent analytical sensitivity, as shown by the linear relationship (0.94 < slope < 1.04, R

Indexed as

Fusion Proteins, bcr-ablLeukemia, Myelogenous, Chronic, BCR-ABL PositiveReference StandardsHumansMutationReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionBCR-ABL1 fusion protein, humanFusion Proteins, bcr-ablBCR-ABL1Chronic myeloid leukemia (CML)One-step reverse transcription dPCRReference materials (RMs)Reference measurement procedure (RMP)

Identifiers

PMID39251426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.