Evidence map›Paper›PMID 39250748›Full record

ArticleNeurology2024

Incident Epilepsy Among US Medicare Beneficiaries, 2019: Differences by Age, Sex, and Race/Ethnicity.

David F Warner, Hannah L Fein, Nicholas K Schiltz, Long Vu, Magdalena Szaflarski, Wyatt P Bensken, Martha Sajatovic, Gena Ghearing, Siran Koroukian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cenobamate for Difficult-to-Treat Epilepsy - Selected Case Vignettes.Neuropsychiatric disease and treatment · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David F WarnerFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.ORCID 0000-0002-8658-2237
Hannah L FeinFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Nicholas K SchiltzFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Long VuFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Magdalena SzaflarskiFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Wyatt P BenskenFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.ORCID 0000-0002-2597-9732
Martha SajatovicFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Gena GhearingFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.
Siran KoroukianFrom the Department of Sociology (D.F.W., M. Szaflarski), University of Alabama at Birmingham; Center for Family & Demographic Research (D.F.W.), Bowling Green State University; Department of Population and Quantitative Health Sciences (H.L.F., L.V., W.P.B., S.K.), Frances Payne Bolton School of Nursing (N.K.S.), and Departments of Psychiatry and Neurology (M. Sajatovic), Case Western Reserve University, Cleveland, OH; and Department of Neurology (G.G.), University of Iowa Health Center, Iowa City.

Funding

NCCDPHP CDC HHS U48 DP006404
6 · The paper itself

Abstract

BACKGROUND AND

objectivesEpilepsy is common among older adults, but previous incident studies have had limited ability to make comparisons across key subgroups. We aimed to provide updated epilepsy incidence estimates among older adults, comparing across age, sex, and race/ethnicity.

methodsUsing a random sample of 4,999,999 US Medicare beneficiaries older than 65 years, we conducted a retrospective cohort study of epilepsy incidence using administrative claims for 2016-2019. Sampled beneficiaries were enrolled in the Fee-for-Service (FFS) program in each of 2016-2018 and had no epilepsy claims in those years. Non-Hispanic Black and Hispanic beneficiaries were oversampled to ensure adequate cases for detailed comparisons. Incidence in 2019 was identified in the Master Beneficiary Summary File as ≥1 inpatient claim or ≥2 outpatient nondrug claims occurring at least 1 day apart (

resultsWe identified 20,545 incident epilepsy cases. The overall epilepsy incidence rate (IR) was 393 per 100,000 (99% CI 385-400). Incidence peaked at ages 85-89 (504 [481-529]) and was higher for men (396 [385-407]) than women (376 [366-385]). The sex difference in IRs was constant with age. Incidence was higher for non-Hispanic Black (678 [653-702]) and Hispanic (405 [384-426]), and lower for non-Hispanic Asian/Pacific Islander (272 [239-305]) beneficiaries, compared with non-Hispanic White beneficiaries (354 [299-408]). The age-specific IRs significantly differed by race/ethnicity and sex, but only among non-Hispanic Black beneficiaries-where men had higher rates at younger ages and women at older ages. DISCUSSION: We found higher epilepsy IRs among those enrolled in the Medicare FFS system 2016-2019 than previous studies using Medicare claims data from at least a decade ago. The risk of epilepsy onset is higher for those in their late 80s, men, and non-Hispanic Black and Hispanic older adults. There is also evidence that these age-graded risks operate differently for Black men and Black women. Efforts to provide care and services that improve quality of life for older adults living with epilepsy should consider differences by multiple social characteristics simultaneously: age, sex, and race/ethnicity.

Indexed as

EpilepsyMedicareAgedAged, 80 and overAge FactorsBlack or African AmericanCohort StudiesEthnicityFemaleHispanic or LatinoHumansIncidenceMaleRacial GroupsRetrospective StudiesSex Factors

Identifiers

PMID39250748
PMCPMC11385955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.