Evidence map›Paper›PMID 39250542›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2024

Mitragynine and morphine produce dose-dependent bimodal action on food but not water intake in rats.

Julio D Zuarth Gonzalez, Marco Mottinelli, Christopher R McCurdy, Guillaume de Lartigue, Lance R McMahon, Jenny L Wilkerson

Abstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Acute fentanyl induces opposing directions of changes in tonic and phasic dopamine release patterns and impairs Pavlovian task performance.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julio D Zuarth GonzalezDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, United States.ORCID 0009-0008-7543-6892
Marco MottinelliDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida, United States.ORCID 0000-0001-5725-0439
Christopher R McCurdyDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida, United States.
Guillaume de LartigueDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, United States.
Lance R McMahonDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, United States.
Jenny L WilkersonDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, United States.ORCID 0000-0002-5594-061X

Funding

Opioid use disorders: UF Pharmacy medications discovery and developmentUH3DA048353 · NIDA · UNIVERSITY OF FLORIDA · PI MCCURDY, CHRISTOPHER R, MCMAHON, LANCE R. · 2021 to 2023
$4.5M
Opioid use disorders: UF Pharmacy medications discovery and developmentUG3DA048353 · NIDA · UNIVERSITY OF FLORIDA · PI MCCURDY, CHRISTOPHER R, MCMAHON, LANCE R. · 2019 to 2020
$3.6M
Nicotine dependence: neuropharmacology in monkeysR01DA025267 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MCMAHON, LANCE R. · 2009 to 2018
$3.4M
HHS | NIH | National Institute on Drug Abuse (NIDA) DA048353HHS | NIH | National Institute on Drug Abuse (NIDA) DA25267NIDA NIH HHS R01 DA025267NIDA NIH HHS UG3 DA048353NIDA NIH HHS UH3 DA048353
6 · The paper itself

Abstract

Kratom (

Indexed as

Dose-Response Relationship, DrugEatingMorphineRats, Sprague-DawleySecologanin Tryptamine AlkaloidsAnalgesics, OpioidAnimalsDrinkingFeeding BehaviorMaleNaltrexoneNarcotic AntagonistsRatsAnalgesics, OpioidmitragynineMorphineNaltrexoneNarcotic AntagonistsSecologanin Tryptamine Alkaloidshormesisingestive behaviorkratomnatural productsopioids

Identifiers

PMID39250542
PMCPMC11687856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.