Evidence map›Paper›PMID 39250422›Full record

ArticleeLife2024

Rifampicin tolerance and growth fitness among isoniazid-resistant clinical

Srinivasan Vijay, Nguyen Le Hoai Bao, Dao Nguyen Vinh, Le Thanh Hoang Nhat, Do Dang Anh Thu, Nguyen Le Quang, Le Pham Tien Trieu, Hoang Ngoc Nhung, Vu Thi Ngoc Ha, Phan Vuong Khac Thai and 6 more

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Within-host evolution of drug tolerance inJAC-antimicrobial resistance · 2026
    Article
  3. Mutations inInfection and drug resistance · 2026
    Article
  4. Variability in intrinsic drug tolerance inAntimicrobial agents and chemotherapy · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Srinivasan Vijay *Oxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.ORCID https://orcid.org/0000-0003-3434-5608
Nguyen Le Hoai Bao *Oxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Dao Nguyen VinhOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Le Thanh Hoang NhatOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Do Dang Anh ThuOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Nguyen Le QuangOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Le Pham Tien TrieuOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Hoang Ngoc NhungOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Vu Thi Ngoc HaOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.
Phan Vuong Khac ThaiPham Ngoc Thach Hospital, Ho Chi Minh, Viet Nam.
Dang Thi Minh HaPham Ngoc Thach Hospital, Ho Chi Minh, Viet Nam.
Nguyen Huu LanPham Ngoc Thach Hospital, Ho Chi Minh, Viet Nam.
Maxine CawsDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Guy E ThwaitesOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.ORCID https://orcid.org/0000-0002-2858-2087
Babak JavidDivision of Experimental Medicine, University of California, San Francisco, San Francisco, United States.
Nguyen Thuy ThuongOxford University Clinical Research Unit, Ho Chi Minh, Viet Nam.ORCID https://orcid.org/0000-0001-8733-692X

Funding

Antibiotic tolerance as a stepping stone to tuberculosis drug-resistanceR21AI169005 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAVID, BABAK · 2023 to 2024
$457k
National Institute of Allergy and Infectious Diseases R21AI169005NIAID NIH HHS R21 AI169005Wellcome TrustWellcome Trust 10.35802/106680Wellcome Trust 10.35802/206724Wellcome Trust 10.35802/207487
6 · The paper itself

Abstract

Antibiotic tolerance in

Indexed as

Antitubercular AgentsDrug Resistance, BacterialIsoniazidMicrobial Sensitivity TestsMycobacterium tuberculosisRifampinHumansLongitudinal StudiesTuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsIsoniazidRifampininfectious diseasemicrobiologymycobacteriumrifampicintolerancetuberculosis

Identifiers

PMID39250422
PMCPMC11383526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.