Evidence map›Paper›PMID 39249627›Full record

ArticleAIDS and behavior2024

Engaging Family Members to Support Exclusive Breastfeeding, Responsive care, and Antiretroviral Therapy Adherence Among Families with Children who are HIV-Exposed and Uninfected.

Tulani Francis L Matenga, Harsh Agarwal, Oluwamuyiwa P Adeniran, Melissa Lam-McCarthy, Enioluwaduroti Abigail Johnson, Josephine Nyambe, Rhoda Chabaputa, Sithembile Chanda, Douglas M Habinda, Laetitia Mulenga and 5 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tulani Francis L MatengaUNC Global Projects Zambia, Lusaka, Zambia.ORCID http://orcid.org/0000-0003-2145-002X
Harsh AgarwalGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Oluwamuyiwa P AdeniranGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Melissa Lam-McCarthyDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Enioluwaduroti Abigail JohnsonGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Josephine NyambeIndependent Consultant, Lusaka, Zambia.
Rhoda ChabaputaUNC Global Projects Zambia, Lusaka, Zambia.
Sithembile ChandaUNC Global Projects Zambia, Lusaka, Zambia.
Douglas M HabindaUNC Global Projects Zambia, Lusaka, Zambia.
Laetitia MulengaUNC Global Projects Zambia, Lusaka, Zambia.
Shimeo SakanyaUNC Global Projects Zambia, Lusaka, Zambia.
Margaret P KasaroUNC Global Projects Zambia, Lusaka, Zambia.ORCID http://orcid.org/0000-0001-7285-998X
Suzanne MamanDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-4048-1585
Benjamin H ChiDepartment of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-1435-8455
Stephanie L MartinDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. slmartin@unc.edu.ORCID http://orcid.org/0000-0002-0378-802X

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Mentoring new investigators in PMTCT implementation researchK24AI120796 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Benjamin H. Chi · 2016 to 2026
$1.3M
Center for AIDS Research, University of North Carolina at Chapel Hill n/aNIAID NIH HHS K24 AI120796NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

Children who are HIV-exposed and uninfected (CHEU) are at increased risk for poor growth, health, and development compared to children who are HIV-unexposed and uninfected. To support families with CHEU, we assessed the acceptability of engaging family members to support women living with HIV (WLWH) with exclusive breastfeeding (EBF) and antiretroviral therapy (ART) adherence and to engage in responsive infant caregiving. We conducted trials of improved practices, a consultative research approach, that follows participants over time as they try recommended behaviors. We enrolled postpartum women in Lusaka, Zambia, who identified home supporters. At visit 1, WLWH were interviewed about current practices. At visit 2, WLWH and home supporters received tailored EBF, responsive care, and ART adherence counseling. At visit 3, WLWH and home supporters were interviewed about their experiences trying recommended practices for 2-3 weeks. Interview transcripts were analyzed thematically. Participants included 23 WLWH, 15 male partners, and 8 female family members. WLWH reported several barriers to EBF. The most common were fear of HIV transmission via breastfeeding-despite high ART adherence-and insufficient breastmilk. After counseling, WLWH reported less fear of HIV transmission and improved breastfeeding practices. Home supporters reported providing WLWH increased support for EBF and ART adherence and practicing responsive caregiving. Both male and female home supporters appreciated being included in counseling and more involved in caregiving, and WLWH valued the increased support. Families with CHEU need focused support. Tailored counseling and family support for WLWH show promise for improving EBF, responsive caregiving, and ART adherence.

Indexed as

Breast FeedingFamilyHIV InfectionsInfectious Disease Transmission, VerticalMedication AdherenceSocial SupportAdultAnti-HIV AgentsAnti-Retroviral AgentsCaregiversCounselingFemaleHumansInfantInfant, NewbornInterviews as TopicAnti-HIV AgentsAnti-Retroviral AgentsART adherenceCounselingEarly child developmentExclusive breastfeedingFamilyHIV-exposed uninfected children

Identifiers

PMID39249627
PMCPMC11586314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.