Evidence map›Paper›PMID 39249626›Full record

Observational studyInternal and emergency medicine2025

Real-world analysis on the use of gamma-hydroxybutyric acid for alcohol withdrawal syndrome in hospitalized patients with diagnosis of cirrhosis.

Monica Salomoni, Andrea Missanelli, Giada Crescioli, Cecilia Lanzi, Arianna Totti, Lorenzo Losso, Stefano Gitto, Roberto Bonaiuti, Alfredo Vannacci, Niccolò Lombardi and 1 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Monica Salomoni *Toxicology Unit and Poison Control Center, Careggi University Hospital, Florence, Italy.
Andrea Missanelli *Toxicology Unit and Poison Control Center, Careggi University Hospital, Florence, Italy.
Giada CrescioliDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy. giada.crescioli@unifi.it.ORCID 0000-0002-1071-6120
Cecilia LanziToxicology Unit and Poison Control Center, Careggi University Hospital, Florence, Italy.
Arianna TottiToxicology Unit and Poison Control Center, Careggi University Hospital, Florence, Italy.
Lorenzo LossoDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
Stefano GittoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Roberto BonaiutiDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
Alfredo VannacciDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
Niccolò Lombardi *Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139, Florence, Italy.
Guido Mannaioni *Toxicology Unit and Poison Control Center, Careggi University Hospital, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present real-world analysis aimed to evaluate and describe the use of gamma-hydroxybutyric acid (GHB) for alcohol withdrawal syndrome (AWS) in hospitalized patients with diagnosis of liver cirrhosis. An 11-year observational retrospective study on patients affected by liver cirrhosis and alcohol use disorder (AUD) was performed using data from the Medical Toxicology Unit of Careggi University Hospital in Florence (Italy). A multivariate logistic regression was performed to estimate the probability of having a CIWA-Ar

Indexed as

HydroxybutyratesLiver CirrhosisSubstance Withdrawal SyndromeAdultAgedAlcoholismFemaleHospitalizationHumansItalyMaleMiddle AgedRetrospective Studies4-hydroxybutyric acidHydroxybutyratesAlcohol withdrawal syndromeClinical practiceGamma-hydroxybutyric acidLiver cirrhosisSodium oxybateToxicology

Identifiers

PMID39249626
PMCPMC11794374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.