Evidence map›Paper›PMID 39249514›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Temperature control during pars plana vitrectomy.

Mario R Romano, Laura Barachetti, Mariantonia Ferrara, Alessandro Mauro, Lorenzo Crepaldi, Valerio Bronzo, Giovanni Franzo, Giuliano Ravasio, Chiara Giudice

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mario R RomanoDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Moltalcini 4, 20072, Pieve Emanuele-Milano, Italy. mario.romano.md@gmail.com.ORCID http://orcid.org/0000-0003-0348-0532
Laura BarachettiPolo Oculistico Veterinario, Milan, Italy.
Mariantonia FerraraEye Unit, ASST Spedali Civili Di Brescia, Brescia, Italy.
Alessandro MauroDepartment of Engineering, University of Naples "Parthenope", Naples, Italy.
Lorenzo CrepaldiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Moltalcini 4, 20072, Pieve Emanuele-Milano, Italy.
Valerio BronzoDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.
Giovanni FranzoDepartment of Animal Medicine, Production and Health, Padua University, Padua, Italy.
Giuliano RavasioDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.
Chiara GiudiceDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca SIR RBSI149484
6 · The paper itself

Abstract

purposeTo evaluate the impact of temperature-controlled pars plana vitrectomy (PPV) on structural and functional outcomes in a rabbit eye model in vivo.

methodsTen healthy New Zealand White rabbits underwent temperature-controlled PPV in the right eye (group A), using a device specifically designed to heat the infusion fluid/air and integrated into the vitrectomy machine, and conventional PPV in the left eye (group B). Both eyes received ophthalmic examination and electroretinography (ERG) before and 1 week postoperatively. After 1-week ERG, rabbits were enucleated and then sacrificed. Histological and immunohistochemical examinations were performed on enucleated eyes and expression of glial fibrillary acidic protein (GFAP) and vimentin investigated.

resultsPostoperatively, only group B showed significantly decreased amplitude and increased latency of a-wave at 3 cd·s/m

conclusionTemperature-controlled PPV resulted in more favorable functional and structural outcomes in rabbit eyes compared with conventional PPV, supporting the potential beneficial role of the intraoperative management of intraocular temperature in vitreoretinal surgery.

Indexed as

Body TemperatureRetinaVitrectomyAnimalsDisease Models, AnimalElectroretinographyGlial Fibrillary Acidic ProteinRabbitsGlial Fibrillary Acidic ProteinHeating deviceHypothermiaIntraocular temperaturePars plana vitrectomyTemperature-controlled pars plana vitrectomyTemperature fluctuations

Identifiers

PMID39249514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.