Evidence map›Paper›PMID 39248462›Full record

ArticleApplied and environmental microbiology2024

Phage-based biocontrol of

Chuncheng Wu, Jumpei Fujiki, Jacques Mathieu, Cory Schwarz, Carolyn Cornell, Pedro J J Alvarez

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Biofilm development ofMicrobiology spectrum · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuncheng WuDepartment of Civil and Environmental Engineering, Rice University, Houston, Texas, USA.ORCID 0009-0007-0719-250X
Jumpei FujikiDepartment of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.ORCID 0000-0002-0476-752X
Jacques MathieuDepartment of Civil and Environmental Engineering, Rice University, Houston, Texas, USA.
Cory SchwarzDepartment of Civil and Environmental Engineering, Rice University, Houston, Texas, USA.ORCID 0000-0002-1802-8357
Carolyn CornellDepartment of Civil and Environmental Engineering, Rice University, Houston, Texas, USA.
Pedro J J AlvarezDepartment of Civil and Environmental Engineering, Rice University, Houston, Texas, USA.ORCID 0000-0002-6725-7199

Funding

Engineering Research Centers (ERC) EEC-1449500
6 · The paper itself

Abstract

Bacteriophages offer an opportunity for chemical-free, precise control of problematic bacteria, but this approach can be limited when lytic phages are difficult to obtain for the target host. In such cases, phage-based targeting of cooperating or cross-feeding bacteria (e.g., IMPORTANCE: Lytic phages are valuable agents for targeted elimination of bacteria in diverse applications. Nevertheless, lytic phages are difficult to isolate for some target pathogens. We offer proof of concept that this limitation may be overcome via indirect phage targeting, which involves knocking out species that interact closely with and benefit the primary problematic target bacteria. Our target (

Indexed as

BacteriophagesBiofilmsPorphyromonas gingivalisStreptococcus gordoniiQuorum Sensingbiofilmindirect targetingpathogen controlphage therapyvirulence

Identifiers

PMID39248462
PMCPMC11497834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.