Evidence map›Paper›PMID 39247802›Full record

ReviewOpen forum infectious diseases2024

The Role of the Gut, Urine, and Vaginal Microbiomes in the Pathogenesis of Urinary Tract Infection in Women and Consideration of Microbiome Therapeutics.

Amal Naji, Drew Siskin, Michael H Woodworth, John R Lee, Colleen S Kraft, Nirja Mehta

Abstract readReview
In one paragraph

Review in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. The Gut-Vagina Axis.Microorganisms · 2026
    Review
  6. Review
  7. Article
  8. Fecal microbiota transplant as treatment for recurrent urinary tract infections: a proof-of-concept study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amal NajiPiedmont Hospital, Atlanta, Georgia, USA.
Drew SiskinEmory University, Atlanta, Georgia, USA.
Michael H WoodworthDivision of Infectious Diseases, Department of Medicine, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-6181-4599
John R LeeDivision of Nephrology and Hypertension, Weill Cornell Medicine, New York, New York, USA.
Colleen S KraftDivision of Infectious Diseases, Department of Medicine, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-1757-8477
Nirja MehtaDivision of Infectious Diseases, Department of Medicine, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-6324-0077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut, urine, and vaginal microbiomes play significant roles in the pathogenesis of recurrent urinary tract infections (rUTIs). Analysis of these microbiota has shown distinct associations with urinary tract infections. Encouraging data indicate that rUTIs may be responsive to microbiome treatments such as fecal microbiota transplantation, expanding potential treatments beyond antibiotics, hydration, and behavioral interventions. If successful, these nonantibiotic therapies have the potential to increase time between rUTI episodes and reduce the prevalence of multidrug-resistant organisms. In this review, we discuss the role of the 3 microbiomes in the pathogenesis of rUTI and utilization of live biotherapeutic products as therapy for rUTI.

Indexed as

bacteriagutmicrobiomeurinaryvaginal

Identifiers

PMID39247802
PMCPMC11378400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.