Evidence map›Paper›PMID 39247509›Full record

ArticleRSC advances2024

New multifunctional hybrids as modulators of apoptosis markers and topoisomerase II in breast cancer therapy: synthesis, characterization, and

Heba W Alhamdi, Mohammad Y Alfaifi, Ali A Shati, Serag Eldin I Elbehairi, Mohammed Er-Rajy, Reda F M Elshaarawy, Yasser A Hassan, Rozan Zakrya

Erratum issuedAbstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Heba W AlhamdiCollege of Sciences, Biology Department, King Khalid University Abha 61413 Saudi Arabia.
Mohammad Y AlfaifiKing Khalid University, Faculty of Science, Biology Department Abha 9004 Saudi Arabia.
Ali A ShatiKing Khalid University, Faculty of Science, Biology Department Abha 9004 Saudi Arabia.
Serag Eldin I ElbehairiKing Khalid University, Faculty of Science, Biology Department Abha 9004 Saudi Arabia.
Mohammed Er-RajyLIMAS Laboratory, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University Fez Morocco.
Reda F M ElshaarawyDepartment of Chemistry, Faculty of Science, Suez University 43533 Suez Egypt reda.elshaarawy@suezuniv.edu.eg.ORCID https://orcid.org/0000-0003-2100-8928
Yasser A HassanDepartment of Pharmaceutics, Faculty of Pharmacy, Delta University for Science and Technology Gamasa Egypt.
Rozan ZakryaChemistry Department, Faculty of Science, Port-Said University Port-Said Egypt rzakrya@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, molecular hybrids of two or more active pharmacophores have shown promise for designing and synthesizing anticancer drugs. Herein, a new multifunctional hybrid (PAHMQ), combining azobenzene and quinoline pharmacophores, and its M(ii) complexes (MPAHMQ) have been successfully developed and structurally characterized. The MTT assay revealed CuBHTP as the most efficient and safe breast cancer treatment, with an IC

Identifiers

PMID39247509
PMCPMC11378026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.