Evidence map›Paper›PMID 39247436›Full record

ArticleSynlett : accounts and rapid communications in synthetic organic chemistry2024

Retrosynthetic Simplicity.

Mark D Levin

Abstract read
In one paragraph

Article in Synlett : accounts and rapid communications in synthetic organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Shape-Conserving Atom Replacements.Chemical reviews · 2026
    Review
  2. Triazenyl Furans as Diels-Alder Dienes.Journal of the American Chemical Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Advancing Total Synthesis Through Skeletal Editing.Accounts of chemical research · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark D LevinDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-4461-363X

Funding

Construction of Heteroarenes Through Single Atom I-RenewalR35GM142768 · NIGMS · UNIVERSITY OF CHICAGO · PI Mark Daniel Levin · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM142768
6 · The paper itself

Abstract

Retrosynthetic simplicity is introduced as a metric by which methods can be evaluated. An argument in favor of reactions which are retrosynthetically simple is put forward, and recent examples in the context of skeletal editing from my own laboratory as well as contributions from others are analyzed critically through this lens.

Indexed as

heterocyclesmethodologyretrosynthesissimplicityskeletal editing

Identifiers

PMID39247436
PMCPMC11377025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.