Evidence map›Paper›PMID 39247221›Full record

ArticleBone reports2024

Trabecular bone score assessed by dual-energy X ray absorption predicts vertebral fractures in HIV infected young adults.

Teresa Mannarino, Adriana D'Antonio, Simona Mercinelli, Maria Falzarano, Federica Volpicelli, Ciro Gabriele Mainolfi, Emanuela Zappulo, Giovanni Di Filippo, Maria Rosaria Cotugno, Ivan Gentile and 1 more

Abstract read
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Article in Bone reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Teresa MannarinoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Simona MercinelliDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.
Maria FalzaranoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Federica VolpicelliDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Ciro Gabriele MainolfiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Emanuela ZappuloDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.
Giovanni Di FilippoDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.
Maria Rosaria CotugnoDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.
Ivan GentileDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bone mineral density (BMD) is reduced in patients with human immunodeficiency virus (HIV) infection. Trabecular bone score (TBS) is an additional feature calculated by dual-energy X ray absorption (DXA) that measures texture inhomogeneity at lumbar spine level, providing an index of bone microarchitecture. However, its clinical value still needs to be fully addressed. Aims of the study were to assess BMD and TBS in a cohort of patients with HIV compared to a population of healthy subjects and to investigate the prognostic value of TBS in HIV infected patients. Method: Bone health was assessed by DXA in 165 patients with HIV infection (120 men, mean age 40 ± 7 years) and in 164 healthy subjects (53 male, mean age 37 ± 10 years). BMD was measured at level of lumbar spine (L1-L4), femoral neck and total hip. TBS was computed from the images of lumbar spine using machine proprietary software. Results: BMD at femoral neck level was similar in HIV infected patients and healthy subjects ( Conclusion: Patients with HIV infection have a significant reduction of TBS, a texture parameter related to bone microarchitecture that may provide skeletal information that is not captured from the standard BMD measurement.

Indexed as

HIVHuman immunodeficiency virusOsteoporosisTrabecular bone score

Identifiers

PMID39247221
PMCPMC11379590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.