Evidence map›Paper›PMID 39246847›Full record

ArticleMolecular and clinical oncology2024

Gastric cancer and brain metastasis: A systematic review and meta‑analysis.

George Fotakopoulos, Grigorios Christodoulidis, Vasiliki Epameinondas Georgakopoulou, Nikolaos Trakas, Pagona Skapani, Konstantinos Panagiotopoulos, Demetrios A Spandidos, Nicolas Foroglou

Abstract read
In one paragraph

Article in Molecular and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

George FotakopoulosDepartment of Neurosurgery, General University Hospital of Larisa, 41221 Larisa, Greece.
Grigorios ChristodoulidisDepartment of General Surgery, General University Hospital of Larisa, 41221 Larisa, Greece.
Vasiliki Epameinondas GeorgakopoulouDepartment of Pathophysiology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Nikolaos TrakasDepartment of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece.
Pagona SkapaniDepartment of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece.
Konstantinos PanagiotopoulosBiochemistry Laboratory, General Hospital of Athens 'Georgios Gennimatas', 11527 Athens, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Nicolas ForoglouFirst Department of Neurosurgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) constitutes one of the most wide-ranging cancers, with brain metastasis (BM) being a markedly uncommon and unfavorable outcome. The present meta-analysis evaluated the relationship between no-surgical treatment vs. additional surgical BM resection on the patient's quality of life and potential survival using electronic databases, including PubMed (1980-April 2024), Medline (1980-April 2024), Cochrane Library, and EMBASE (1980-April 2024). After a literature search, six articles were included in the final study pool. The number of patients with BM and conservative treatment was 289 (80.05%) compared with those that underwent an additional surgical resection 72 (19.95%). The mean age was 59.2 years, and the males were 195 (73.8%) of 264 available from five studies. The findings of the present meta-analysis revealed that the curative effect of BM tumor resection on patients with GC undergoing additional treatment with stereotactic radiosurgery, whole-brain radiotherapy or chemotherapy was favorable for their survival.

Indexed as

brain metastasisconservative or no-surgical treatmentgastric cancersurgical resectionsurvival outcomes

Identifiers

PMID39246847
PMCPMC11375760

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