Evidence map›Paper›PMID 39246796›Full record

ArticleSurgical neurology international2024

Cerebrospinal fluid protein concentration in patients with lumbar spinal stenosis.

Hitoshi Yamahata, Kosei Ijiri, Fumito Tanabe, Kyoichi Murasumi, Yushi Nagano, Ryutaro Makino, Nayuta Higa, Ryosuke Hanaya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hitoshi YamahataDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kirishima, Kagoshima, Japan.
Kosei IjiriDepartment of Orthopaedics, Kirishima Orthopaedics, Kirishima, Kagoshima, Japan.
Fumito TanabeDepartment of Orthopaedics, Kirishima Orthopaedics, Kirishima, Kagoshima, Japan.
Kyoichi MurasumiDepartment of Orthopaedics, Kirishima Orthopaedics, Kirishima, Kagoshima, Japan.
Yushi NaganoDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kirishima, Kagoshima, Japan.
Ryutaro MakinoDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kirishima, Kagoshima, Japan.
Nayuta HigaDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kirishima, Kagoshima, Japan.
Ryosuke HanayaDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kirishima, Kagoshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration. Methods: In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B). Results: The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block. Conclusion: A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.

Indexed as

Cerebrospinal fluidLumbar spinal stenosisLumbar spineProtein concentration

Identifiers

PMID39246796
PMCPMC11380900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.