ReviewImmune network2024
A Dynamic Interplay of Innate Immune Responses During Urinary Tract Infection.
Review in Immune network, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Urinary tract infections in children.Nature reviews. Urology · 2026Review
- The effect of toll like receptors in prognosis in patients undergoing radical cystectomy for bladder cancer.Molecular biology reports · 2026Article
- Combined predictive accuracy of inflammatory and hematologic indicators for urinary tract-related bloodstream infection.American journal of translational research · 2026Article
- Prevalence, Etiology, and Antibiotic Resistance Patterns of Urinary Tract Infections in a Baghdad Hospital: Focus on UropathogenicInternational journal of microbiology · 2026Article
- Autophagy-driven MHC-I downregulation enables NK cell-mediated clearance of intracellular uropathogenicAnimal cells and systems · 2026Article
- The immune mechanisms of the urinary tract against infections.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urinary tract infections (UTIs) represent one of the most prevalent bacterial infections globally, manifesting in diverse clinical phenotypes with varying degrees of severity and complications. The mechanisms underlying UTIs are gradually being elucidated, leading to an enhanced understanding of the immune responses involved. Innate immune cells play a crucial defensive role against uropathogenic bacteria through various mechanisms. Despite their significant contributions to host defense, these cells often fail to achieve complete clearance of uropathogens, necessitating the frequent prescription of antibiotics for UTI patients. However, the persistence of infections and related pathological symptoms in the absence of innate immune cells in animal models underscore the importance of innate immunity in UTIs. Therefore, the host protective functions of innate immune cells, including neutrophils, macrophages, mast cells, NK cells, innate lymphoid cells, and γδ T cells, are delicately coordinated and timely regulated by a variety of cytokines to ensure successful pathogen clearance.
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Registered trials
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