Evidence map›Paper›PMID 39246613›Full record

ArticleOxford medical case reports2024

Thymoma with recurrent opportunistic infections-a case report.

Sri Lasya Karjala, Satya Prasad Namala, Phani Krishna Machiraju, Prabu Pandurangan

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sri Lasya KarjalaDepartment of General Medicine, Apollo Hospitals, Chennai 600 006, Tamilnadu, India.ORCID https://orcid.org/0000-0003-3971-9082
Satya Prasad NamalaDepartment of Hematology, Apollo Hospitals, Chennai 600 006, Tamilnadu, India.ORCID https://orcid.org/0009-0000-9867-5038
Phani Krishna MachirajuDepartment of Hematology, Apollo Hospitals, Chennai 600 006, Tamilnadu, India.ORCID https://orcid.org/0000-0002-9721-6996
Prabu PanduranganDepartment of Hematology, Apollo Hospitals, Chennai 600 006, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Good's syndrome (GS) is a rare adult-onset thymoma associated with acquired combined B-cell and T-cell immunodeficiency. It has similarities with Common variable immunodeficiency (CVID) in terms of hypogammaglobulinemia and significant risk of invasive bacterial and opportunistic infections. We still have a long way to go in understanding the pathogenesis of Good's syndrome. Here, we describe a case of a middle-aged female with thymoma and recurrent opportunistic infections. Clinico-laboratory evaluation led to a diagnosis of GS and she showed good response to intravenous immunoglobulin. Clinicians should be aware that thymoma can precede the onset of immunodeficiency.

Indexed as

good’s syndromehypogammaglobulinemiaopportunistic infectionsthymoma

Identifiers

PMID39246613
PMCPMC11380083

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.