Evidence map›Paper›PMID 39245803›Full record

ArticlePhysiological reports2024

Maximal respiratory pressure after COVID-19 compared with reference material in healthy adults: A prospective cohort study (The SECURe study).

Thora Wesenberg Helt, Jan Christensen, Ronan M G Berg, Thomas Kromann Lund, Anna Kalhauge, Frederikke Rönsholt, Daria Podlekareva, Elisabeth Arndal, Flemming Madsen, Mathias Munkholm and 4 more

Abstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thora Wesenberg HeltDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-3763-8839
Jan ChristensenDepartment of Occupational Therapy and Physiotherapy, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Ronan M G BergDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-5757-9506
Thomas Kromann LundDepartment of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Anna KalhaugeDepartment of Radiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Frederikke RönsholtDepartment of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Daria PodlekarevaDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Elisabeth ArndalDepartment of Otorhinolaryngology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Flemming MadsenCenter for Clinical Research and Prevention, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Mathias MunkholmDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Birgitte HanelDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Anne-Mette LebechDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Terese Lea KatzensteinDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Jann MortensenDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After COVID-19 long term respiratory symptoms and reduced lung function including maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) have been reported. However, no studies have looked at MIP and MEP in all disease groups and the reference materials collection methods differ substantially. We aimed to determine MIP and MEP in individuals after COVID-19 infection with different disease severity using reference material of healthy control group obtained using the same standardized method. Patients with COVID-19 were included March 2020-March 2021 at Rigshospitalet, Denmark. MIP and MEP were measured using microRPM. Predicted MIP and MEP were calculated using reference material obtained from 298 healthy adults aged 18-97 years using the same method. In SECURe, 145 participants were measured median 5 months after COVID-19 diagnosis and of these 16% had reduced MIP and/or MEP. There was reduced spirometry and total lung capacity, but not reduced diffusion capacity in those with abnormal MIP and/or MEP compared with normal MIP and MEP. Of those with reduced MIP and/or MEP at 5 months, 80% still had reduced MIP and/or MEP at 12 months follow-up. In conclusion, few have reduced MIP and/or MEP 5 months after COVID-19 and little improvement was seen over time.

Indexed as

COVID-19Maximal Respiratory PressuresAdolescentAdultAgedAged, 80 and overDenmarkFemaleHumansLungMaleMiddle AgedProspective StudiesSARS-CoV-2Young AdultCOVID‐19DALFUMATrespiratory muscle strength, reference values, SECURe

Identifiers

PMID39245803
PMCPMC11381190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.