Evidence map›Paper›PMID 39245785›Full record

Observational studyChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Impact of hemispherotomy on quality of life and burden of caregivers in children and adolescents: a retrospective observational study.

Bruna Frizzera Daniel, Suenia Timotheo Figueiredo Leal, Américo Ceiki Sakamoto, Ursula Thomé, Hélio Rubens Machado, Marcelo Volpon Santos, Antônio Carlos Dos Santos, Ana Paula Andrade Hamad

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bruna Frizzera DanielRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Suenia Timotheo Figueiredo LealRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Américo Ceiki SakamotoRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Ursula ThoméRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Hélio Rubens MachadoRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Marcelo Volpon SantosRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Antônio Carlos Dos SantosRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Ana Paula Andrade HamadRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil. anahamad@fmrp.usp.br.

Funding

Partial financial support was received from FAEPA (Fundação de apoio ao ensino, pesquisa e assistência) - HCFMRP - USP, Brazil. 1024/2021
6 · The paper itself

Abstract

purposeTo evaluate QOL and caregiver burden of children and teenagers submitted to hemispherotomy for pharmacoresistant epilepsy, by comparing pre and post-surgical intervention data. MATERIALS AND

methodsRetrospective analysis of pediatric patients submitted to surgical hemispherotomy before intervention (preOP) and their follow-up at 6 months (6 M PO) and 2 years (2Y PO) after surgery. QOL was evaluated through the Quality of Life in Childhood Epilepsy (QVCE-50) questionnaire and caregiver burden, through the Zarit Burden Interview (ZBI) tool.

resultsTwenty-two patients were included in the study. Sixteen patients (72%) were classified as Engel I at 2Y PO follow-up. QVCE-50 scale showed improvement of total QOL at 2Y PO. In relation to QVCE-50-specific domains, there was an improvement in the physical domain and in the cognitive-education a decrease in psychological and a stabilization in social/familiar domain scores. The majority of caregivers classified their burden as mild to moderate, with no PO improvement.

conclusionsHemispherotomy represents an effective seizure control treatment, as well as it contributes to improvement of QOL, particularly in the physical domain and in spite of children's physical and cognitive limitations. However, no improvement in caregiver burden was observed, probably due to the chronic condition of these patients, which might be worsened by social issues.

Indexed as

CaregiversHemispherectomyQuality of LifeAdolescentCaregiver BurdenChildChild, PreschoolCost of IllnessDrug Resistant EpilepsyFemaleHumansMaleRetrospective StudiesSurveys and QuestionnairesTreatment OutcomeAdolescentsCaregiver burdenChildrenEpilepsyHemispherotomyQuality of life

Identifiers

PMID39245785

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.