Evidence map›Paper›PMID 39245681›Full record

ArticleNature communications2024

TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma.

Kaifan Bao, Xiaoqun Gu, Yajun Song, Yijing Zhou, Yanyan Chen, Xi Yu, Weiyuan Yuan, Liyun Shi, Jie Zheng, Min Hong

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Group 2 innate lymphoid cells: Where are we 15 years out?The Journal of allergy and clinical immunology · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Population-scale Long-read Sequencing in themedRxiv : the preprint server for health sciences · 2025
    Article
  10. Article
  11. Review
  12. The role of innate immune system in respiratory viral infection related asthma.Frontiers in cellular and infection microbiology · 2025
    Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kaifan BaoJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. bkf0824@njucm.edu.cn.ORCID 0000-0001-7344-9368
Xiaoqun GuJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yajun SongJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yijing ZhouJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yanyan ChenJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Xi YuNanjing Haikerui Pharmaceutical Technology Co., LTD, Nanjing, 210023, China.
Weiyuan YuanJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Liyun ShiDepartment of Immunology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jie ZhengJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. jessiezheng@njucm.edu.cn.ORCID 0000-0001-7601-9152
Min HongJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. minhong@njucm.edu.cn.ORCID 0000-0002-2086-8937

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82074087National Natural Science Foundation of China (National Science Foundation of China) 82204714Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) BK20191414
6 · The paper itself

Abstract

Immune memory has been expanded to group 2 innate lymphoid cells (ILC2s), but the cellular and molecular bases remain incompletely understood. Based on house dust mite (HDM)-induced mice asthma models and human samples, we applied flow cytometry, parabiosis, in vivo imaging and adoptive transplantation to confirm the persistence, migration and function of CD45

Indexed as

AsthmaHepatocyte Nuclear Factor 1-alphaHomeodomain ProteinsImmunity, InnateImmunologic MemoryLymphocytesAdoptive TransferAnimalsDisease Models, AnimalFemaleHumansInterleukin-13Intestinal MucosaIntestinesIntestine, SmallMaleHepatocyte Nuclear Factor 1-alphaHnf1a protein, mouseHomeodomain ProteinsInterleukin-13Rhox8 protein, mouse

Identifiers

PMID39245681
PMCPMC11381517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.