ArticleNeurologia medico-chirurgica2024
Correlation between Delayed Relief after Microvascular Decompression and Morphology of the Lateral Spread Response in Patients with Hemifacial Spasm-Further Examination with Compound Motor Action Potentials.
Article in Neurologia medico-chirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Etiological analysis and reoperative strategies for recurrent or failed hemifacial spasm after microvascular decompression.Neurosurgical review · 2026Article
- Reassessing the Role of the Subarcuate Artery in Hearing Preservation during Microvascular Decompression.Neurologia medico-chirurgica · 2025Article
- The application value of intraoperative lateral spreading response monitoring during microvascular decompression in patients with primary hemifacial spasm.European journal of medical research · 2025Article
- The glabella tap reflex reveals fluctuations in the hyperexcitability of the facial nucleus with hemifacial spasm: a prospective observational study.Neurosurgical review · 2025Observational
- Intraoperative use of lateral spread response measurement in the upper orbicularis oculi and mandibular muscles in patients with hemifacial spasm after botulinum toxin treatment.Acta neurochirurgica · 2025Article
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Abstract
Although microvascular decompression (MVD) is a reliable treatment for hemifacial spasm (HFS), postoperative delayed relief is one of its main issues. We previously evaluated the morphology of the lateral spread response (LSR) and reported correlation between delayed relief after MVD and polyphasic morphology of the LSR. This study aimed to investigate the morphology of LSR and the course of recovery of the compound motor action potential (CMAP), to better understand the pathophysiology of delayed healing of HFS. Based on the pattern of the initial LSR morphology on temporal and marginal mandibular branches stimulation, patients were divided into two groups: the monophasic and polyphasic groups. The results of MVD surgery and sequential changes in the CMAP were evaluated 1 week, 1 month, 1 year, and final follow-up after the surgery. Significantly higher rates of persistent postoperative HFS were observed in patients with the polyphasic type of initial LSR at 1 week and 1 month after the surgery (P < 0.05, respectively). In the polyphasic group, the amplitude of the CMAP tended to gradually improve with time, while in the monophasic group, the amplitude of the CMAP decreased on the seventh postoperative day, followed by its gradual improvement. There is a significant correlation between delayed relief after MVD and polyphasic morphology of the initial LSR in patients with HFS. In the polyphasic group, CMAP recovered earlier and showed less reduction in amplitude, suggesting segmental demyelination, with less damage to peripheral nerves.
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