Evidence map›Paper›PMID 39245405›Full record

ArticleResuscitation2024

Resuscitation of patients with durable mechanical circulatory support with acutely altered perfusion or cardiac arrest: A scoping review.

Ari Moskowitz, Helen Pocock, Anthony Lagina, Kee Chong Ng, Barnaby R Scholefield, Carolyn M Zelop, Janet Bray, Joseph Rossano, Nicholas J Johnson, Joel Dunning and 8 more

Abstract readScoping Review
In one paragraph

Article in Resuscitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ari MoskowitzDivision of Critical Care, Montefiore Medical Center, the Bronx, NY United States; Bronx Center for Critical Care Outcomes and Resuscitation Research, the Bronx, NY, United States. Electronic address: amoskowitz@montefiore.org.
Helen PocockSouth Central Ambulance NHS Foundation Trust, Bicester, United Kingdom; Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Anthony LaginaWayne State University, Detroit, MI, United States.
Kee Chong NgKK Women's and Children's Hospital, Singapore.
Barnaby R ScholefieldThe Hospital for Sick Children, Toronto, Canada.
Carolyn M ZelopValley Health System, Paramus, NJ, Untied States; NYU Grossman School of Medicine, New York, NY, United States.
Janet BrayMonash University, Melbourne, Australia.
Joseph RossanoChildren's Hospital of Philadelphia, Philadelphia, PA, United States.
Nicholas J JohnsonDepartment of Emergency Medicine & Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA.
Joel DunningJames Cook University Hospital, Middlesbrough, United Kingdom.
Theresa OlasveengenOslo University Hospital and University of Oslo, Oslo, Norway.
Tia RaymondMedical City Children's Hospital, Dallas, Texas.
David L S MoralesHeart Institute at Cincinnati Childrens Hospital, Cincinnati, United States.
Anthony CarleseDivision of Critical Care, Montefiore Medical Center, the Bronx, NY United States.
Marie EliasMontefiore Medical Center Health Sciences Library, the Bronx, NY, United States.
Katherine M BergBeth Israel Deaconess Medical Center, Boston, MA, United States.
Ian DrennanUniversity of Toronto, Toronto, Canada.
ILCOR Advanced Life Support, Basical Life Support, and Pediatric Life Support Task Forces

Funding

Hospital Airway Resuscitation TrialR33HL162980 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Ari Moskowitz · 2023 to 2026
$3.3M
NHLBI NIH HHS R33 HL162980
6 · The paper itself

Abstract

backgroundThere is an increasing prevalence of durable mechanical circulatory supported patients in both the in-and-out of hospital communities. The scientific literature regarding the approach to patients supported by durable mechanical circulatory devices who suffer acutely impaired perfusion has not been well explored.

methodsThe International Liaison Committee on Resuscitation Advanced, Basic, and Pediatric Life Support Task Forces conducted a scoping review of the literature using a population, context, and concept framework.

resultsA total of 32 publications that included patients who were receiving durable mechanical circulatory support and required acute resuscitation were identified. Most of the identified studies were case reports or small case series. Of these, 11 (34.4%) included patients who received chest compressions. A number of studies reported upon delays in the application of chest compressions resulting from complexity due to the expected pulselessness in some patients with continuous flow left-ventricular assist devices as well as from concern regarding potential dislodgement of the mechanical circulatory support device. Three observational studies identified worse outcomes in durable mechanical circulatory support receiving patients with cardiac arrest and acutely impaired perfusion who received chest compressions as compared to those who did not, however those studies were at high risk of bias. Of 226 patients across 11 studies and two published scientific abstracts who sustained cardiac arrest while supported by durable MCS and underwent chest compressions, there were no reported instances of device dislodgement and 71 (31.4%) patients had favorable outcomes.

conclusionsThere is a scarcity of evidence to inform the resuscitation of patients with durable mechanical circulatory support (MCS) experiencing acute impairment in perfusion and cardiac arrest. Reports indicate that delays in resuscitation often stem from rescuers' uncertainty about the safety of administering chest compressions. Notably, no instances of device dislodgement have been documented following chest compressions, suggesting that the risk of harm from timely CPR in these patients is minimal.

Indexed as

Cardiopulmonary ResuscitationHeart ArrestHeart-Assist DevicesHumansCardiac ArrestLeft Ventricular Assist DeviceMechanical Circulatory Support

Identifiers

PMID39245405
PMCPMC11466699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.