Evidence map›Paper›PMID 39244817›Full record

ArticlePregnancy hypertension2024

Hyperaldosteronism secondary to renal agenesis: An unusual cause for hypertension in pregnancy.

Nalini Newbigging, Sowmya Sathyendra, Sudha Jasmine, Liji S David, Audrin Lenin, Jennifer David Livingstone, Nihal Thomas, Remya Rajan, Suceena Alexander

Abstract readCase Reports
In one paragraph

Article in Pregnancy hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nalini NewbiggingDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: nalini.newbigging@cmcvellore.ac.in.
Sowmya SathyendraDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Medicine Unit 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: sowmya@cmcvellore.ac.in.
Sudha JasmineDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Medicine Unit 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: sudhajasmine@cmcvellore.ac.in.
Liji S DavidObstetrics and Gynaecology Unit 4, Vellore, Tamil Nadu, India. Electronic address: Liji.David@cmcvellore.ac.in.
Audrin LeninDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Department of Medicine 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: audrinlenin@cmcvellore.ac.in.
Jennifer David LivingstoneDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Department of Medicine 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: jennifer.david.pg@cmcvellore.ac.in.
Nihal ThomasDepartment of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: nihal_thomas@cmcvellore.ac.in.
Remya RajanDepartment of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: remya.rajan@cmcvellore.ac.in.
Suceena AlexanderDepartment of Nephrology Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: suceena@cmcvellore.ac.in.

Funding

DBT-Wellcome Trust India Alliance IA/CPHS/22/1/506541
6 · The paper itself

Abstract

Literature with regards to pregnancy related outcomes in persons with the presence of a solitary kidney of any cause is scarce. Most of the available information has been extrapolated from persons who have been renal donors. Unilateral renal agenesis affects 1 in 1500 people and can present with resistant hypertension. When a woman with a solitary kidney presents in pregnancy, it may be both a challenging diagnostic and therapeutic problem. Eplerenone, a selective aldosterone blocker has been prescribed for resistant hypertension and in the presence of pregnancy, been useful in persons with primary hyperaldosteronism and resistant hypertension due to obstructive sleep apnoea. We describe the use of Eplerenone in a patient with resistant hypertension in pregnancy, due to secondary hyperaldosteronism precipitated by renal agenesis.

Indexed as

HyperaldosteronismSolitary KidneyAdultAntihypertensive AgentsCongenital AbnormalitiesEplerenoneFemaleHumansHypertension, Pregnancy-InducedKidneyKidney DiseasesMineralocorticoid Receptor AntagonistsPregnancySpironolactoneAntihypertensive AgentsEplerenoneMineralocorticoid Receptor AntagonistsSpironolactoneEplerenonePregnancyRenal agenesisResistant hypertensionSecondary hyperaldosteronism

Identifiers

PMID39244817
PMCPMC7616660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.