ArticleNature communications2024
Molecular epidemiology and evolutionary characteristics of dengue virus 2 in East Africa.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Severe Dengue in Children: Pathogenesis, Early Recognition, and Evidence-Informed Management.Tropical medicine and infectious disease · 2026Review
- Global, regional, and national impact of epidemic disasters on health workforce equality between 1990 and 2019: An ecological and modeling study.PLoS medicine · 2026Article
- Genomic investigation reveals local persistence and regional circulation of dengue virus associated with recent outbreaks in Kenya.Scientific reports · 2026Article
- Genomic epidemiology reveals the origins and transmission dynamics of chikungunya virus in China.Infectious diseases of poverty · 2026Article
- Genomic Evidence for Novel Introduction and Intra-Host Diversity of DENV-2 in Dar es Salaam, Tanzania.Viruses · 2026Article
- Biobanking of vector-borne viruses in the Philippines: basic principles, best practices, and challenges.Scientific reports · 2026Article
- Designing a multi-epitope vaccine against dengue virus-2 usingBioImpacts : BI · 2026Article
- Evolutionary history and transmission dynamics of dengue virus type 2 in Africa.Frontiers in microbiology · 2026Article
- Dengue virus serotype 4 in Aedes aegypti mosquitoes in Kenya.PLoS neglected tropical diseases · 2025Article
- Sociodemographic and ecological factors associated with malaria and malaria recurrence risk in children in Msambweni, Kwale County, Kenya.Malaria journal · 2025Article
- Risk factors associated with dengue and chikungunya seroprevalence and seroconversion among urban populations in western and coastal Kenya.PLoS neglected tropical diseases · 2025Article
- Decoding Dengue: A Global Perspective, History, Role, and Challenges.Pathogens (Basel, Switzerland) · 2025Review
- Temporal Variation and Human Host Predominance inPathogens (Basel, Switzerland) · 2025Article
- Non-household environments make a major contribution to dengue transmission: implications for vector control.Royal Society open science · 2025Article
- Comparison of unmanned aerial vehicle imaging to ground truth walkthroughs for identifying and classifying trash sites serving as potential Aedes aegypti breeding grounds.Parasites & vectors · 2025Article
- Genomic characterization and evolution analysis of peste des petits ruminants virus in China from 2007 to 2024.Frontiers in microbiology · 2025Article
- Geographic origin and evolution of dengue virus serotypes 1 and 3 circulating in Africa.Virus evolution · 2025Article
Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
Despite the increasing burden of dengue, the regional emergence of the virus in Kenya has not been examined. This study investigates the genetic structure and regional spread of dengue virus-2 in Kenya. Viral RNA from acutely ill patients in Kenya was enriched and sequenced. Six new dengue-2 genomes were combined with 349 publicly available genomes and phylogenies used to infer gene flow between Kenya and other countries. Analyses indicate two dengue-2 Cosmopolitan genotype lineages circulating in Kenya, linked to recent outbreaks in coastal Kenya and Burkina Faso. Lineages circulating in Western, Southern, and Eastern Africa exhibiting similar evolutionary features are also reported. Phylogeography suggests importation of dengue-2 into Kenya from East and Southeast Asia and bidirectional geneflow. Additional lineages circulating in Africa are also imported from East and Southeast Asia. These findings underscore how intermittent importations from East and Southeast Asia drive dengue-2 circulation in Kenya and Africa more broadly.
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