Evidence map›Paper›PMID 39244554›Full record

Trial reportBMC primary care2024

Enhancing hypertension education of community health extension workers in Nigeria's federal capital territory: the impact of the extension for community healthcare outcomes model on primary care, a quasi-experimental study.

Abigail S Baldridge, Ikechukwu A Orji, Gabriel L Shedul, Guhan Iyer, Erica L Jamro, Jiancheng Ye, Blessing O Akor, Emmanuel Okpetu, Samuel Osagie, Adaora Odukwe and 6 more

Registry-linked trialAbstract readMulticenter StudyClinical Trial
In one paragraph

Trial report in BMC primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04158154 (Transforming Hypertension Treatment in Nigeria Using a Type II Hybrid, Interrupted Time Series Design), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04158154 nacompletednot on this map

Transforming Hypertension Treatment in Nigeria Using a Type II Hybrid, Interrupted Time Series Design

TypeinterventionalSponsorWashington University School of MedicineRan2020 to 2023Enrolled21,922ConditionsHypertensionArmsEvidence-based fixed-dose combination protocol based treatment
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. ANDES trial and integration of the HEARTS model in Puno, Peru.Revista panamericana de salud publica = Pan American journal of public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Abigail S BaldridgeFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA. abigail.baldridge@northwestern.edu.
Ikechukwu A OrjiUniversity of Abuja Teaching Hospital, Abuja, Nigeria.
Gabriel L ShedulFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA.
Guhan IyerWashington University in St. Louis, St. Louis, MO, USA.
Erica L JamroWashington University in St. Louis, St. Louis, MO, USA.
Jiancheng YeFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA.
Blessing O AkorUniversity of Abuja Teaching Hospital, Abuja, Nigeria.
Emmanuel OkpetuUniversity of Abuja Teaching Hospital, Abuja, Nigeria.
Samuel OsagieUniversity of Abuja, Abuja, Nigeria.
Adaora OdukwemDoc Healthcare, Lagos, Nigeria.
Haulat Olabisi DabirimDoc Healthcare, Lagos, Nigeria.
L Nneka MobissonmDoc Healthcare, Lagos, Nigeria.
Namratha R KandulaFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA.
Lisa R HirschhornFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA.
Mark D HuffmanFeinberg School of Medicine, Northwestern University, 676 N St. Clair St. Suite 1700, Chicago, IL, 60611, USA.
Dike B OjjiUniversity of Abuja Teaching Hospital, Abuja, Nigeria.

Funding

Transforming Hypertension Management in NigeriaR01HL144708 · NHLBI · WASHINGTON UNIVERSITY · PI Mark D Huffman, Dike Bevis Ojji · 2019 to 2026
$4.3M
NHLBI NIH HHS R01 HL144708NHLBI NIH HHS R01HL144708Northwestern Bluhm Cardiovascular Institute NANorthwestern Robert J. Havey MD Institute for Global Health NAResolve to Save Lives NA
6 · The paper itself

Abstract

backgroundHealthcare workers (HCWs) including community health extension workers (CHEWs) in the Federal Capital Territory, Nigeria participated in a hypertension training series following the Extension for Community Healthcare Outcomes (ECHO) model which leverages technology and a practical peer-to-peer learning framework to virtually train healthcare practitioners. We sought to evaluate the patient-level effects of the hypertension ECHO series.

methodsHCWs from 12 of 33 eligible primary healthcare centers (PHCs) in the Hypertension Treatment in Nigeria Program (NCT04158154) were selected to participate in a seven-part hypertension ECHO series from August 2022 to April 2023. Concurrent Hypertension Treatment in Nigeria Program patient data were used to evaluate changes in hypertension treatment and control rates, and adherence to Nigeria's hypertension treatment protocol. Outcomes were compared between the 12 PHCs in the ECHO program and the 21 which were not.

resultsBetween July 2022 and June 2023, 16,691 PHC visits were documented among 4340 individuals (ECHO: n = 1428 [33%], non-ECHO: n = 2912 [67%]). Patients were on average (SD) 51.5 (12.0) years old, and one-third were male (n = 1372, 32%) with no differences between cohorts in either characteristic (p ≥ 0.05 for both). Blood pressures at enrollment were higher in the ECHO cohort compared to the non-ECHO cohort (systolic p < 0.0001 and diastolic p = 0.0001), and patients were less likely to be treated with multiple medications (p < 0.0001). Treatment rates were similar at baseline (ECHO: 94.0% and Non-ECHO: 94.7%) and increased at a higher rate (interaction p = 0.045) in the ECHO cohort over time. After adjustment for baseline and within site variation, the difference was attenuated (interaction p = 0.37). Over time, control rates increased and medication protocol adherence decreased, with no differences between cohorts. Staffing levels, adult patient visits, and rates of hypertension screening and empanelment were similar between ECHO and non-ECHO cohorts (p ≥ 0.05 for all).

conclusionsThe ECHO series was associated with moderately increased hypertension treatment rates and did not adversely affect staffing or clinical capacity among PHCs in the Federal Capital Territory, Nigeria. These results may be used to inform strategies to support scaling hypertension education among frontline HCWs throughout Nigeria, and use of the ECHO model for CHEWs.

trial registrationThe Hypertension Treatment in Nigeria Program was prospectively registered on November 8, 2019 at www. CLINICALTRIALS: gov (NCT04158154; https://clinicaltrials.gov/ct2/show/NCT04158154 ).

Indexed as

Community Health WorkersHypertensionPrimary Health CareAdultAntihypertensive AgentsFemaleHumansMaleMiddle AgedNigeriaAntihypertensive AgentsEducationHypertensionImplementationPrimary careQualitative

Identifiers

PMID39244554
PMCPMC11380766

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.