Evidence map›Paper›PMID 39244515›Full record

ArticleAnnals of surgical oncology2024

Differences in Prognosis and Recurrence Patterns Between Ulcerative Colitis-Associated Colorectal Cancer and Sporadic Colorectal Cancer: A Matched-Pair Analysis.

Kei Kobayashi, Kenichiro Toritani, Hideaki Kimura, Jun Kawashima, Koki Goto, Yusuke Suwa, Mayumi Ozawa, Asushi Ishibe, Jun Watanabe, Itaru Endo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kei KobayashiInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Kenichiro ToritaniInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Hideaki KimuraInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan. hkim@yokohama-cu.ac.jp.
Jun KawashimaInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Koki GotoInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Yusuke SuwaDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
Mayumi OzawaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Asushi IshibeDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Jun WatanabeDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Itaru EndoDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinicopathological differences exist between ulcerative colitis-associated colorectal cancer (UC-CRC) and sporadic colorectal cancer (S-CRC). However, differences in the prognosis remain controversial, and the reason for these differences remains unclear. We therefore assessed the differences between patients with UC-CRC and S-CRC. PATIENTS AND

methodsThis was a matched-pair analysis of the clinicopathological characteristics and prognosis of patients with UC-CRC and S-CRC who underwent colorectal resection between January 2000 and December 2021 at two institutions. Patients were matched according to age, sex, date of surgery, tumor location, and Union for International Cancer Control (UICC) stage.

resultsA total of 5992 patients underwent surgery for CRC at the two institutions, and 288 patients (48 with UC-CRC and 240 with S-CRC) were matched in this study. Patients with UC-CRC underwent more invasive surgery and had a longer operative time than those with S-CRC, but there was no marked difference in postoperative complications or perioperative mortality. Long-term outcomes showed a similar 5-year overall survival (OS) for UC-CRC and S-CRC (86.5% versus 88.8%, p = 0.742); however, in stage 3 patients, patients with UC-CRC had a poorer 5-year OS than those with S-CRC (51.4% versus 83.8%, p = 0.032). The first recurrence sites in stage 3 UC-CRC were peritoneal dissemination followed by the bones, while those in S-CRC were the liver and pulmonary system.

conclusionsDespite no significant differences in surgical outcomes, patients with UC-CRC had a poorer prognosis than those with S-CRC at stage 3. The recurrence patterns in UC-CRC differed from those in S-CRC, suggesting a possible prognostic difference.

Indexed as

Colitis, UlcerativeColorectal NeoplasmsNeoplasm Recurrence, LocalAdultAgedFemaleFollow-Up StudiesHumansMaleMatched-Pair AnalysisMiddle AgedNeoplasm StagingPostoperative ComplicationsPrognosisRetrospective StudiesSurvival RatePrognosisRecurrence patternsSporadic colorectal cancerUlcerative colitisUlcerative colitis-associated colorectal cancer

Identifiers

PMID39244515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.