Evidence map›Paper›PMID 39243765›Full record

ArticleCell2024

Divergent sensory pathways of sneezing and coughing.

Haowu Jiang, Huan Cui, Mengyu Chen, Fengxian Li, Xiaolei Shen, Changxiong J Guo, George E Hoekel, Yuyan Zhu, Liang Han, Kangyun Wu and 2 more

Abstract read
In one paragraph

Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Sulfolipid-1 fromJournal of neurophysiology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Cracking the Code of the Jugular Vagal Sensory Neurons in Allergic Airway Responsiveness.American journal of respiratory cell and molecular biology · 2025
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Haowu JiangDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Huan CuiDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Mengyu ChenDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Fengxian LiDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Xiaolei ShenDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Changxiong J GuoDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
George E HoekelDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Yuyan ZhuThe School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Liang HanThe School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Kangyun WuPulmonary and Critical Care Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Michael J HoltzmanPulmonary and Critical Care Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Qin LiuDepartment of Anesthesiology, Washington University Pain Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA. Electronic address: qinliu@wustl.edu.

Funding

Defining and Controlling Airway DiseaseR35HL145242 · NHLBI · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2019 to 2025
$6.6M
The Neural Basis of Ocular SensationsR01EY024704 · NEI · WASHINGTON UNIVERSITY · PI LIU, QIN · 2014 to 2024
$4.3M
PARP9-DTX3L Control Of Viral Infection and Airway DiseaseR01AI130591 · NIAID · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2017 to 2021
$3.0M
The Neural Mechanism of Respiratory Allergies and InfectionsR01AI163146 · NIAID · WASHINGTON UNIVERSITY · PI LIU, QIN · 2021 to 2025
$2.6M
The function of MrgprC11+ vagal sensory neurons in the airwayR01HL141269 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAN, LIANG · 2018 to 2022
$1.9M
Neural Circuits Controlling LacrimationR01EY035261 · NEI · WASHINGTON UNIVERSITY · PI Qin Liu · 2023 to 2026
$1.9M
NEI NIH HHS R01 EY024704NEI NIH HHS R01 EY035261NHLBI NIH HHS R01 HL141269NHLBI NIH HHS R35 HL145242NIAID NIH HHS R01 AI130591NIAID NIH HHS R01 AI163146
6 · The paper itself

Abstract

Sneezing and coughing are primary symptoms of many respiratory viral infections and allergies. It is generally assumed that sneezing and coughing involve common sensory receptors and molecular neurotransmission mechanisms. Here, we show that the nasal mucosa is innervated by several discrete populations of sensory neurons, but only one population (MrgprC11

Indexed as

CoughSneezingAnimalsFemaleHumansMaleMiceMice, Inbred C57BLNasal MucosaReceptors, G-Protein-CoupledSensory Receptor CellsTracheaReceptors, G-Protein-Coupledallergycoughingrespiratory viral infectionsensory neuronssneezing

Identifiers

PMID39243765
PMCPMC11622829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.