Evidence map›Paper›PMID 39243314›Full record

ReviewPediatric radiology2025

Radiological features in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease-diagnostic criteria and lesion dynamics.

Li-Tal Pratt, Hadas Meirson, Mika Shapira Rootman, Liat Ben-Sira, Shelly I Shiran

Abstract readReview
In one paragraph

Review in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li-Tal PrattPediatric Radiology, Imaging Division, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel. litalp@tlvmc.gov.il.ORCID 0009-0008-4576-086X
Hadas MeirsonSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-1836-5679
Mika Shapira RootmanThe Department of Diagnosing Imaging, Rambam Medical Center, Haifa, Israel.ORCID 0000-0002-6758-7673
Liat Ben-SiraPediatric Radiology, Imaging Division, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.ORCID 0000-0002-0827-0190
Shelly I ShiranPediatric Radiology, Imaging Division, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.ORCID 0000-0001-5166-5107

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spectrum of acquired pediatric demyelinating syndromes has been expanding over the past few years, to include myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), as a distinct neuroimmune entity, in addition to pediatric-onset multiple sclerosis (POMS) and aquaporin 4-IgG-seropositive neuromyelitis optica spectrum disorder (AQP4+NMOSD). The 2023 MOGAD diagnostic criteria require supporting clinical or magnetic resonance imaging (MRI) features in patients with low positive myelin oligodendrocyte glycoprotein IgG titers or when the titers are not available, highlighting the diagnostic role of imaging in MOGAD. In this review, we summarize the key diagnostic features in MOGAD, in comparison to POMS and AQP4+NMOSD. We describe the lesion dynamics both during attack and over time. Finally, we propose a guideline on timing of imaging in clinical practice.

Indexed as

AutoantibodiesDemyelinating Autoimmune Diseases, CNSMagnetic Resonance ImagingMyelin-Oligodendrocyte GlycoproteinChildDiagnosis, DifferentialHumansMyelin Oligodendrocyte Glycoprotein Antibody-Associated DiseaseAutoantibodiesMyelin-Oligodendrocyte GlycoproteinAcute disseminated encephalomyelitisAquaporin 4-IgG-seropositive neuromyelitis optica spectrum disorderDemyelinating diseasesMagnetic resonance imagingMultiple sclerosisMyelin oligodendrocyte glycoprotein antibody-associated diseaseOptic neuritisTransverse myelitis

Identifiers

PMID39243314
PMCPMC11982100

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.