Evidence map›Paper›PMID 39242805›Full record

ArticleCommunications psychology2024

Positive affect modulates memory by regulating the influence of reward prediction errors.

Salman E Qasim, Aarushi Deswal, Ignacio Saez, Xiaosi Gu

Abstract read
In one paragraph

Article in Communications psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Salman E QasimDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-8739-5962
Aarushi DeswalThe Winsor School, Boston, MA, USA.
Ignacio SaezCenter for Computational Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-0651-2069
Xiaosi GuDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. xiaosi.gu@mssm.edu.ORCID http://orcid.org/0000-0002-9373-987X

Funding

Computational and electrochemical substrates of social decision-making in humansR01MH124115 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GU, XIAOSI, KISHIDA, KENNETH TUCKER · 2020 to 2024
$5.1M
Invasive decoding and stimulation of altered reward computations in depressionR01MH124763 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAEZ, IGNACIO · 2021 to 2025
$3.9M
Neurocomputational mechanisms of proactive social behavior deficits in autism spectrum disorderR01MH122611 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FOSS-FEIG, JENNIFER, GU, XIAOSI · 2020 to 2024
$3.9M
Neural, computational and behavioral characterization of dynamic social behavior in borderline and avoidant personality disorderR01MH123069 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI, KOENIGSBERG, HAROLD W · 2021 to 2025
$3.1M
Computational and Neural Modeling of Cue Reactivity in AddictionR01DA043695 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI · 2018 to 2022
$2.9M
Delineating proactive social behaviors in dynamic and multidimensional social spaceR21MH120789 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI, SCHILLER, DANIELA · 2019 to 2020
$466k
Neurocomputational Mechanisms for Addiction Heterogeneity, Impulsivity and PerseveranceR21DA049243 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI · 2019 to 2020
$466k
The computational and neural mechanisms linking decision-making and memory in humansK99MH132873 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI QASIM, SALMAN EHTESHAM · 2023 to 2024
$120k
NIDA NIH HHS R01 DA043695NIDA NIH HHS R21 DA049243NIMH NIH HHS K99 MH132873NIMH NIH HHS R01 MH122611NIMH NIH HHS R01 MH123069NIMH NIH HHS R01 MH124115NIMH NIH HHS R01 MH124763NIMH NIH HHS R21 MH120789U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) K99MH132873
6 · The paper itself

Abstract

How our decisions impact our memories is not well understood. Reward prediction errors (RPEs), the difference between expected and obtained reward, help us learn to make optimal decisions-providing a signal that may influence subsequent memory. To measure this influence and how it might go awry in mood disorders, we recruited a large cohort of human participants to perform a decision-making task in which perceptually memorable stimuli were associated with probabilistic rewards, followed by a recognition test for those stimuli. Computational modeling revealed that positive RPEs enhanced both the accuracy of memory and the temporal efficiency of memory search, beyond the contribution of perceptual information. Critically, positive affect upregulated the beneficial effect of RPEs on memory. These findings demonstrate how affect selectively regulates the impact of RPEs on memory, providing a computational mechanism for biased memory in mood disorders.

Identifiers

PMID39242805
PMCPMC11332028

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.