Evidence map›Paper›PMID 39242698›Full record

ArticleCommunications biology2024

Metagenomic analysis reveals high diversity of gut viromes in yaks (Bos grunniens) from the Qinghai-Tibet Plateau.

Xiang Lu, Ga Gong, Qing Zhang, Shixing Yang, Haisheng Wu, Min Zhao, Xiaochun Wang, Quan Shen, Likai Ji, Yuwei Liu and 6 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

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0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Molecular Characterization ofAnimals : an open access journal from MDPI · 2026
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  4. Review
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  6. Article
  7. Article
  8. Article
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  13. Viral Metagenomics of the Bharal (Polish journal of microbiology · 2025
    Article
  14. Article
  15. Viral metagenomic analysis of fecal samples fromFrontiers in cellular and infection microbiology · 2025
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiang Lu *Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID 0000-0003-2987-9664
Ga Gong *Animal Science College, Tibet Agriculture and Animal Husbandry University, Nyingchi, Tibet, China.
Qing Zhang *Qinghai Institute of Endemic Disease Prevention and Control, Xining, China.
Shixing Yang *Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Haisheng WuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Min ZhaoDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Xiaochun WangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Quan ShenDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Likai JiDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Yuwei LiuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Yongshun WangQinghai Institute of Endemic Disease Prevention and Control, Xining, China.
Jia LiuQinghai Institute of Endemic Disease Prevention and Control, Xining, China.
Sizhu SuolangAnimal Science College, Tibet Agriculture and Animal Husbandry University, Nyingchi, Tibet, China. xzslsz@163.com.ORCID 0000-0001-6286-2296
Xiao MaQinghai Institute of Endemic Disease Prevention and Control, Xining, China. maxiao0971@163.com.ORCID 0009-0008-9358-2279
Tongling ShanShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China. shantongling@shvri.ac.cn.ORCID 0000-0002-5329-6349
Wen ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China. zhangwen@ujs.edu.cn.ORCID 0000-0002-9352-6153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Qinghai-Tibet Plateau (QTP), renowned for its exceptional biological diversity, is home to numerous endemic species. However, research on the virology of vulnerable vertebrates like yaks remains limited. In this study, our objective was to use metagenomics to provide a comprehensive understanding of the diversity and evolution of the gut virome in yak populations across different regions of the QTP. Our findings revealed a remarkably diverse array of viruses in the gut of yaks, including those associated with vertebrates and bacteriophages. Notably, some vertebrate-associated viruses, such as astrovirus and picornavirus, showed significant sequence identity across diverse yak populations. Additionally, we observed differences in the functional profiles of genes carried by the yak gut virome across different regions. Moreover, the virus-bacterium symbiotic network that we discovered holds potential significance in maintaining the health of yaks. Overall, this research expands our understanding of the viral communities in the gut of yaks and highlights the importance of further investigating the interactions between viruses and their hosts. These data will be beneficial for revealing the crucial role that viruses play in the yak gut ecology in future studies.

Indexed as

Gastrointestinal MicrobiomeMetagenomicsViromeAnimalsCattleMetagenomeTibet

Identifiers

PMID39242698
PMCPMC11379701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.