Evidence map›Paper›PMID 39242618›Full record

ArticleScientific data2024

KORE-Map 1.0: Korean medicine Omics Resource Extension Map on transcriptome data of tonifying herbal medicine.

Musun Park, Sang-Min Park, Haeseung Lee, Aeyung Kim, No Soo Kim, Yu Ri Kim, Jin-Mu Yi, Seongwon Cha

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Musun Park *Korean Medicine (KM) Data Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-5383-5285
Sang-Min Park *College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.ORCID 0000-0003-2915-0742
Haeseung Lee *College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Aeyung KimKM Application Center, Korea Institute of Oriental Medicine, Daegu, Republic of Korea.
No Soo KimKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Yu Ri KimKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Jin-Mu YiKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. jmyi@kiom.re.kr.
Seongwon ChaKorean Medicine (KM) Data Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. scha@kiom.re.kr.

Funding

Korea Institute of Oriental Medicine (KIOM) KSN1722122
6 · The paper itself

Abstract

Traditional herbal medicine, rooted in a long history of use in East Asia, combines several herbs to create treatments showing high efficacy with minimal side effects, for specific diseases. Such combination therapies represent a potential reservoir of new drugs for treating multifactorial and incurable chronic diseases. However, the complexity of their mechanisms of action due to the combination of multiple compounds, has limited their research integration into modern pharmacological science. To address this challenge, we constructed drug-induced transcriptome data for herbal medicines through systematic experiments, analyzed with the aid of various omics databases. We introduce KORE-Map 1.0 (Korean medicine Omics Resource Extension Map), the first comprehensive resource of drug-derived transcriptome data for representative tonifying herbal medicines, effective in enhancing the immune system. This dataset aims to provide novel insights into the combinatorial mechanisms of these herbal medicines and to aid in the discovery of new therapeutic targets and indications for various incurable diseases.

Indexed as

TranscriptomeHerbal MedicineHumansMedicine, Korean TraditionalPlants, Medicinal

Identifiers

PMID39242618
PMCPMC11379693

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.