Evidence map›Paper›PMID 39242598›Full record

ArticleJournal of eating disorders2024

Association between childhood maltreatment and obsessive-compulsive disorder comorbid with eating disorders: a cross-sectional study.

Salma Attar, Jinane Jomaah, Rhéa El Khoury, Colin Cordahi, Maude Seneque, Philippe Courtet, Rami Bou Khalil, Sebastien Guillaume

Abstract read
In one paragraph

Article in Journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Salma Attar *Faculty of Pharmacy, Saint-Joseph University, Beirut, Lebanon.
Jinane Jomaah *Department of Psychiatry, Faculty of Medicine, Saint Joseph University, Achrafieh, Beirut, Lebanon.
Rhéa El KhouryDepartment of Psychiatry, Faculty of Medicine, Saint Joseph University, Achrafieh, Beirut, Lebanon.
Colin CordahiDepartment of Psychiatry, Faculty of Medicine, Saint Joseph University, Achrafieh, Beirut, Lebanon.
Maude SenequeInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Philippe CourtetInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Rami Bou KhalilDepartment of Psychiatry, Faculty of Medicine, Saint Joseph University, Achrafieh, Beirut, Lebanon. rami.boukhalil@usj.edu.lb.ORCID https://orcid.org/0000-0003-1725-4755
Sebastien GuillaumeInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObsessive-compulsive disorder (OCD) and eating disorders (ED) share common features, including the presence of obsessions and compulsions, and they often co-occur. Additionally, there is a significant comorbidity between ED and childhood traumatic experiences (CTE), as well as between CTE and OCD. Various biological and environmental factors have been proposed to explain the connection between ED, OCD, and CTE. This study explores the link between CTE and the comorbidity of ED and OCD, with the hypothesis that specific types of CTE may increase the risk of developing OCD in individuals with ED.

methodsParticipants (N = 562) were enrolled at an eating disorder unit in Montpellier, France, between March 2013 and January 2020. The Childhood Trauma Questionnaire (CTQ), Eating Disorder Examination Questionnaire (EDE-Q), and Mini International Neuropsychiatric Interview (MINI) were used to evaluate childhood maltreatment, assess clinical characteristics associated with ED, and categorize participants into two groups: patients with and without OCD.

resultsBivariate analysis revealed that patients with comorbid ED and OCD had higher EDE-Q scores (p < 0.001), more anxiety disorders (p < 0.001), depressive disorders (p = 0.02), post-traumatic stress disorder (PTSD) (p < 0.001), and a higher incidence of sexual abuse (p < 0.001) and physical neglect (p = 0.04) compared to those without OCD. Multivariate analysis showed that the association between CTE and OCD was influenced by the presence of an anxiety disorder (p = 0.01) and a higher EDE-Q total score (p = 0.03), with a significant association with a history of sexual abuse (p = 0.04).

conclusionsThis demonstrates that CTE increases the risk of comorbid OCD in ED patients, correlating with more clinically severe ED and a higher likelihood of anxiety disorders.

Indexed as

Childhood traumatic experiencesComorbidityEating disorderObsessive-compulsive disorderSexual abuseTrauma

Identifiers

PMID39242598
PMCPMC11380211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.