Evidence map›Paper›PMID 39242569›Full record

ArticleNature communications2024

Destabilized near-infrared fluorescent nanobodies enable background-free targeting of GFP-based biosensors for imaging and manipulation.

Natalia V Barykina, Erin M Carey, Olena S Oliinyk, Axel Nimmerjahn, Vladislav V Verkhusha

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Programmable nanobody circuits for cell selection.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalia V BarykinaDepartment of Genetics, and Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, NY, 10461, USA.ORCID 0000-0001-5835-8388
Erin M CareyWaitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
Olena S OliinykMedicum, Faculty of Medicine, University of Helsinki, Helsinki, 00290, Finland.
Axel NimmerjahnWaitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.ORCID 0000-0002-0875-7855
Vladislav V VerkhushaDepartment of Genetics, and Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, NY, 10461, USA. vladislav.verkhusha@einsteinmed.edu.

Funding

Spinal Circuits for the Control of Dextrous MovementU19NS112959 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI AZIM, EIMAN · 2019 to 2023
$14.3M
Novel Genetically Encoded Indicators for Interrogating Neuron-Astrocyte Communication Across TimescalesU19NS123719 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TIAN, LIN · 2021 to 2025
$10.7M
Near-Infrared Fluorescent Proteins, Biosensors and Optogenetic ToolsR35GM122567 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Vladislav Verkhusha · 2017 to 2026
$4.3M
NIGMS NIH HHS R35 GM122567NINDS NIH HHS U19 NS112959NINDS NIH HHS U19 NS123719U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health (OER) GM122567
6 · The paper itself

Abstract

Near-infrared (NIR) probes are highly sought after as fluorescent tags for multicolor cellular and in vivo imaging. Here we develop small NIR fluorescent nanobodies, termed NIR-Fb

Indexed as

Biosensing TechniquesGreen Fluorescent ProteinsMice, TransgenicSingle-Domain AntibodiesAnimalsCalciumFluorescent DyesHEK293 CellsHumansMiceSomatosensory CortexSpectroscopy, Near-InfraredCalciumFluorescent DyesGreen Fluorescent ProteinsSingle-Domain Antibodies

Identifiers

PMID39242569
PMCPMC11379940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.