Evidence map›Paper›PMID 39242526›Full record

ArticleBMC urology2024

The role of early use of Carbapenems perioperatively for urolithiasis with ESBL-producing Escherichia coli.

Zhilin Li, Donglong Cheng, Huacai Zhu, Mehmet Ali Karagöz, Chonghe Jiang, Shilin Zhang, Yongda Liu

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In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zhilin Li *Department of Urology, Foshan Women and Children Hospital, Foshan, Guangdong, China.
Donglong Cheng *Department of Urology, Jiangmen Central Hospital, Jiangmen, Guangdong, China.
Huacai Zhu *Department of Urology, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, China.
Mehmet Ali KaragözDepartment of Urology, Kafkas University Faculty of Medicine, Kars, Turkey.
Chonghe JiangDepartment of Urology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan, China.
Shilin ZhangDepartment of Urology, Foshan Women and Children Hospital, Foshan, Guangdong, China. zhang_40_1@163.com.
Yongda LiuDepartment of Urology, Guangdong Key Laboratory of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Kangda Road 1#, Haizhu District, Guangzhou, 510230, Guangdong, China. 13719007083@163.com.

Funding

Foshan Science and Technology Agency 2320001006380Guangdong Basic and Applied Basic Research Foundation 2020A1515011461the Science and Technology Plan Program of Guangzhou 202201020511
6 · The paper itself

Abstract

backgroundUrolithiasis combined with ESBL-producing E. coli is often difficult to control and leads to higher postoperative infection-related complications. This study was aim to explore the efficacy and necessity for early use of carbapenem antibiotics perioperatively in urolithiasis patients with urinary tract infections caused by ESBL-producing E. coli.

methodsThe study included a total of 626 patients who were separated into two groups: Group I (the ESBL-producing E. coli group) and Group II (the non-ESBL-producing E. coli group). Antibiotic susceptibility testing was performed and the two groups induced postoperative infection-related events were recorded. the efficacy of perioperative antibiotics was evaluated.

resultsAll strains of E. coli in our research were sensitive to Carbapenems antibiotics. In addition to Carbapenems, the resistance rates of ESBL-producing E. coli to 6 other commonly used antibiotics were higher than those of non-ESBL-producing strains. Based on the preoperative antibiotic susceptibility test for the ESBL-producing E. coli group and the qSOFA score, the Carbapenems were more effective than the β-lactamase inhibitors (p = 0.08), while for the non-ESBL-producing E. coli group, there was no difference in the treatment effects between Carbapenems, β-lactamase inhibitors, Ceftazidime and Quinolones (p = 0.975).

conclusionsCarbapenem antibiotics significantly reduced the incidence of postoperative infection-related events compared with other types of antibiotics for ESBL-producing E. coli infections in patient with urolithiasis.

Indexed as

beta-LactamasesCarbapenemsEscherichia coliEscherichia coli InfectionsUrolithiasisAdultAgedAnti-Bacterial AgentsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedPerioperative CareRetrospective StudiesTreatment OutcomeAnti-Bacterial Agentsbeta-LactamasesCarbapenemsEscherichia coliUrinary tract infectionsUrolithiasis

Identifiers

PMID39242526
PMCPMC11378573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.