Evidence map›Paper›PMID 39242410›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

The effect of nasopharyngeal obstruction on the olfactory bulb volume and olfactory sulcus depth in children : First author.

Linyin Yao, Jia Liu, Xiaoli Yi, Qinglong Gu

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Linyin YaoDepartment of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jia LiuDepartment of Otolaryngology Head and Neck Surgery, The Affiliated Children's Hospital, Capital Institute of Pediatrics, Yabao Road 2, Beijing, 100020, China.
Xiaoli Yi *Department of Radiology, The Affiliated Children's Hospital, Capital Institute of Pediatrics, Yabao Road 2, Beijing, 100020, China. xiaoli_yi@126.com.ORCID http://orcid.org/0009-0001-6125-0746
Qinglong Gu *Department of Otolaryngology Head and Neck Surgery, The Affiliated Children's Hospital, Capital Institute of Pediatrics, Yabao Road 2, Beijing, 100020, China. gql71@163.com.

Funding

Beijing Municipal Natural Science Foundation 7232010Capital Health Research and Development of Special Fund 2022-1-2101Research Foundation of Capital Institute of Pediatrics JHYJ-2025-02
6 · The paper itself

Abstract

purposeSmell ability is associated with nasopharyngeal obstruction. Herein, we evaluated the effect of nasopharyngeal obstruction by adenoid hypertrophy on the olfactory bulb (OB) volume and olfactory sulcus (OS) depth in children.

methodsA total of 135 children who were candidates for brain magnetic resonance imagining scanning were enrolled in the study. The olfactory disorder-negative statements questionnaire was utilized to assess the patient-reported olfactory status. A validated sleep questionnaire was used to assess sleeping status. According to the adenoidal/nasopharyngeal (A/N) ratio, the children were divided into two groups: those with an A/N ratio ≤ 0.5 (n = 70) and those with an A/N ratio > 0.5 (n = 65). OB volume and OS depth measurements were performed on coronal T2-weighted images using planimetric manual contouring. The mean OB volumes and OS depths on the right and left sides were used for the evaluation.

resultsThe mean OB volume of the group with an A/N ratio > 0.5 was significantly lower than that of the group with an A/N ratio ≤ 0.5 (P = 0.003), while there was no difference in the mean OS depth between groups (P = 0.061). In those with an A/N ratio > 0.5, the mean OB volume in older children (aged 9-12 years) was significantly lower than that in younger children (aged 5-8 years) (P = 0.012). In terms of laterality, the OS depth on the right side was significantly larger than that on the left side in both groups (P = 0.039 and P = 0.001). In the group with an A/N ratio ≤ 0.5, the OB volume on the right side was also significantly larger than that on the left side (P = 0.040); however, no such difference was observed in the group with an A/N ratio > 0.5 (P = 0.630). No sex-based differences were evident for any variable.

conclusionsChildren with nasopharyngeal obstruction greater than 50% have a significantly smaller OB volume. Our results suggest that morphological alterations in OB may contribute to the pathogenic mechanism of olfactory dysfunction related to nasopharyngeal obstruction.

Indexed as

AdenoidsHypertrophyMagnetic Resonance ImagingOlfactory BulbAdolescentAirway ObstructionChildChild, PreschoolFemaleHumansMaleNasopharyngeal DiseasesNasopharynxOlfaction DisordersOrgan SizeSurveys and QuestionnairesMRINasopharyngeal obstructionOlfactory bulbOlfactory sulcus

Identifiers

PMID39242410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.