Evidence map›Paper›PMID 39242376›Full record

ArticleResults and problems in cell differentiation2024

The Biological Significance of Trogocytosis.

Deborah Agbakwuru, Scott A Wetzel

Abstract read
In one paragraph

Article in Results and problems in cell differentiation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Deborah AgbakwuruCenter for Environmental Health Sciences, University of Montana, Missoula, MT, USA.
Scott A WetzelCenter for Environmental Health Sciences, University of Montana, Missoula, MT, USA. scott.wetzel@umontana.edu.

Funding

Characterizing the contribution of trogocytosis to T Follicular Helper differentiation and humoral immune responsesR15AI147034 · NIAID · UNIVERSITY OF MONTANA · PI WETZEL, SCOTT A · 2020 to 2020
$432k
NIAID NIH HHS R15 AI147034
6 · The paper itself

Abstract

Trogocytosis is the intercellular transfer of membrane and membrane-associated proteins between cells. Trogocytosis is an underappreciated phenomenon that has historically routinely been dismissed as an artefact. With a greater understanding of the process and the implications it has on biological systems, trogocytosis has the potential to become a paradigm changer. The presence on a cell of molecules they don't endogenously express can alter the biological activity of the cell and could also lead to the acquisition of new functions. To better appreciate this phenomenon, it is important to understand how these intercellular membrane exchanges influence the function and activity of the donor and the recipient cells. In this chapter, we will examine how the molecules acquired by trogocytosis influence the biology of a variety of systems including mammalian fertilization, treatment of hemolytic disease of the newborn, viral and parasitic infections, cancer immunotherapy, and immune modulation.

Indexed as

Cell MembraneAnimalsHumansCancer immunotherapyEmbryonic developmentFertilizationIntercellular transferTransendocytosisTrogocytosisTrogocytosis-mediated signaling

Identifiers

PMID39242376
PMCPMC11784324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.