Evidence map›Paper›PMID 39242170›Full record

ArticleBMJ open2024

Mixed-methods protocol for the WiSSPr study: Women in Sex work, Stigma and psychosocial barriers to Pre-exposure prophylaxis in Zambia.

Ramya Kumar, Deepa Rao, Anjali Sharma, Jamia Phiri, Martin Zimba, Maureen Phiri, Ruth Zyambo, Gwen Mulenga Kalo, Louise Chilembo, Phidelina Milambo Kunda and 6 more

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ramya KumarCentre for Infectious Disease Research in Zambia, Lusaka, Zambia ramya.kumar.mlk@gmail.com.ORCID 0000-0002-4570-6686
Deepa RaoUniversity of Washington School of Public Health, Seattle, Washington, USA.ORCID 0000-0003-4076-0170
Anjali SharmaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID 0000-0002-8189-0732
Jamia PhiriCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Martin ZimbaZambia Sex Workers Alliance, Lusaka, Zambia.
Maureen PhiriZambia Sex Workers Alliance, Lusaka, Zambia.
Ruth ZyamboTithandizeni Umoyo Network, Lusaka, Zambia.
Gwen Mulenga KaloTithandizeni Umoyo Network, Lusaka, Zambia.
Louise ChilemboTithandizeni Umoyo Network, Lusaka, Zambia.
Phidelina Milambo KundaLusaka District Health Office, Zambia Ministry of Health, Lusaka, Zambia.
Chama MulubwaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Benard NgosaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Kenneth K MugwanyaEpidemiology, Global Health, University of Washington School of Public Health, Seattle, Washington, USA.ORCID 0000-0001-5208-7468
Wendy E BarringtonEpidemiology; Child, Family, and Population Health Nursing; Health Systems and Population Health, University of Washington School of Public Health, Seattle, Washington, USA.
Michael E HerceCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID 0000-0002-3629-3867
Maurice MushekeCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID 0000-0001-9968-7540

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
FIC NIH HHS D43 TW009340
6 · The paper itself

Abstract

introductionWomen engaging in sex work (WESW) have 21 times the risk of HIV acquisition compared with the general population. However, accessing HIV pre-exposure prophylaxis (PrEP) remains challenging, and PrEP initiation and persistence are low due to stigma and related psychosocial factors. The WiSSPr (Women in Sex work, Stigma and PrEP) study aims to (1) estimate the effect of multiple stigmas on PrEP initiation and persistence and (2) qualitatively explore the enablers and barriers to PrEP use for WESW in Lusaka, Zambia. METHODS AND ANALYSIS: WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry of Health (MoH). We will administer a one-time psychosocial survey vetted by the CAB and follow 300 WESW in the electronic medical record for three months to measure PrEP initiation (#/% ever taking PrEP) and persistence (immediate discontinuation and a medication possession ratio). We will conduct in-depth interviews with a purposive sample of 18 women, including 12 WESW and 6 peer navigators who support routine HIV screening and PrEP delivery, in two community hubs serving KPs since October 2021. We seek to value KP communities as equal contributors to the knowledge production process by actively engaging KP-CSOs throughout the research process. Expected outcomes include quantitative measures of PrEP initiation and persistence among WESW, and qualitative insights into the enablers and barriers to PrEP use informed by participants' lived experiences. ETHICS AND DISSEMINATION: WiSSPr was approved by the Institutional Review Boards of the University of Zambia (#3650-2023) and University of North Carolina (#22-3147). Participants must give written informed consent. Findings will be disseminated to the CAB, who will determine how to relay them to the community and stakeholders.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSex WorkersSocial StigmaAdultAnti-HIV AgentsCommunity-Based Participatory ResearchFemaleHumansObservational Studies as TopicProspective StudiesResearch DesignZambiaAnti-HIV AgentsEPIDEMIOLOGIC STUDIESHealth EquityHIV & AIDSMENTAL HEALTHQUALITATIVE RESEARCHSOCIAL MEDICINE

Identifiers

PMID39242170
PMCPMC11381648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.