Evidence map›Paper›PMID 39242090›Full record

Trial reportEndoscopy2025

Prospective single-arm trial on feasibility and safety of an endoscopic robotic system for colonic endoscopic submucosal dissection.

Philip W Y Chiu, Hon Chi Yip, Simon Chu, Shannon M Chan, Ho Shing Louis Lau, Raymond S Y Tang, Soo Jay Phee, Khek Yu Ho, Simon Siu Man Ng

Abstract readClinical TrialVideo-Audio Media
In one paragraph

Trial report in Endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Ethical and Legal Implications of Implementing AI in Gastrointestinal Endoscopy.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  7. Review
  8. [Current Status of Robotic Therapeutic Endoscopic Platforms].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Philip W Y ChiuSurgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-9292-112X
Hon Chi YipSurgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0003-1041-9668
Simon ChuSurgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Shannon M ChanSurgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-6280-4176
Ho Shing Louis LauInstitute of Digestive Disease and State Key Laboratory of GI Diseases, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0002-4163-4531
Raymond S Y TangInstitute of Digestive Disease and State Key Laboratory of GI Diseases, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Soo Jay PheeSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.
Khek Yu HoGastroenterology and Hepatology, National University of Singapore Yong Loo Lin School of Medicine, Singapore, Singapore.
Simon Siu Man NgSurgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of the EndoMaster "Endoluminal Access Surgical Efficacy" (EASE) system aims to enhance the safety and efficacy of colonic endoscopic submucosal dissection (ESD) through two flexible robotic arms. This is the first clinical trial to evaluate the performance of colorectal ESD using EndoMaster.

methodPatients with early mucosal colorectal neoplasia that was not suitable for en bloc resection with snare-based techniques were recruited. The EndoMaster EASE robotic system consisted of an independently designed flexible robotic platform with two robotic arms. The primary outcome was the complete resection rate using EndoMaster. Secondary outcomes included operating time, hospital stay, procedure-related complications, and oncologic outcomes.

results43 patients underwent robotic ESD, with a median robotic dissection time of 49 minutes. The technical success rate was 86.0%, while en bloc resection rate among cases with technical success was 94.6%. The complete resection rate was 83.8% and the median size of specimen was 35 mm (range 15-90 mm). The median hospital stay was 2 (range 1-7) days and there was one delayed bleed after 4 days, which was controlled endoscopically. One patient sustained perforation during the procedure, which was completely closed using clips without sequelae. Two patients were treated by salvage surgery.

conclusionThis first clinical trial confirmed the safety and efficacy of performing colorectal ESD using the EndoMaster EASE robotic system.

Indexed as

ColonoscopyColorectal NeoplasmsEndoscopic Mucosal ResectionRobotic Surgical ProceduresAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansLength of StayMaleMiddle AgedOperative TimeProspective StudiesTreatment Outcome

Identifiers

PMID39242090
PMCPMC11867098

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.