Evidence map›Paper›PMID 39241276›Full record

ReviewCurrent opinion in microbiology2024

Biofilms as more than the sum of their parts: lessons from developmental biology.

Georgia R Squyres, Dianne K Newman

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Dissecting the physics of bacterial biofilms with agent-based simulations.Current opinion in solid state & materials science · 2025
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Georgia R SquyresDivision of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
Dianne K NewmanDivision of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA; Division of Geological and Planetary Sciences, Caltech, Pasadena, CA 91125, USA. Electronic address: dkn@caltech.edu.

Funding

Biological mechanisms and consequences of efficient extracellular electron transfer in Pseudomonas aeruginosaR01AI127850 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Dianne K Newman · 2017 to 2026
$5.6M
NIAID NIH HHS R01 AI127850
6 · The paper itself

Abstract

Although our understanding of both bacterial cell physiology and the complex behaviors exhibited by bacterial biofilms is expanding rapidly, we cannot yet sum the behaviors of individual cells to understand or predict biofilm behavior. This is both because cell physiology in biofilms is different from planktonic growth and because cell behavior in biofilms is spatiotemporally patterned. We use developmental biology as a guide to examine this phenotypic patterning, discussing candidate cues that may encode spatiotemporal information and possible roles for phenotypic patterning in biofilms. We consider other questions that arise from the comparison between biofilm and eukaryotic development, including what defines normal biofilm development and the nature of biofilm cell types and fates. We conclude by discussing what biofilm development can tell us about developmental processes, emphasizing the additional challenges faced by bacteria in biofilm development compared with their eukaryotic counterparts.

Indexed as

BacteriaBacterial Physiological PhenomenaBiofilmsDevelopmental BiologyPhenotype

Identifiers

PMID39241276
PMCPMC12124288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.